苗潇磊
讲师
研究领域
熟练掌握各种生化分析仪器的使用,尤其是LC-MS/MS 中药主要活性物质的提取、纯化、分离与鉴定 熟练掌握动物实验操作、相关生化指标检测、体内外药物分析与药代动力学研究
近期论文
1. Xiaolei Miao, Junjun Wang, Liang Chen, Zhihong Peng, Yong Chen*. Identification of in vivo and in vitro metabolites of 4,5-dimethoxycanthin-6-one by UPLC-Q-TOF-MS/MS[J]. Journal of Chromatography B, 2016, 1020: 78-84.(SCI 3区,IF2.687) 2. Xiaolei Miao, Junjun Wang, Yong Chen*. Pharmacokinetics and tissue distribution of 4,5-dimethoxycanthin-6-one and its major metabolites in rats[J]. Journal of Pharmaceutical and Biomedical Analysis, 2017, 139:22-29.(SCI 3区,IF3.169) 3. Xiaolei Miao, Jiaojiao You, Junjun Wang, Yong Chen*. In vitro metabolism of 4, 5-dimethoxycanthin-6-one by human liver microsomes and its inhibition on human CYP1A2[J]. Life Sciences, 2017, 190: 46-51.(SCI 3区,IF2.936) 4. Liang Chen1, Xiaolei Miao1, Zhihong Peng, Junjun Wang, Yong Chen*. The pharmacokinetics and bioavailability of three canthinone alkaloids after administration of Kumu injection to rats[J]. Journal of Ethnopharmacology, 2016, 182: 235-241.(SCI 3区,IF3.055) 5. Jun-jun W 1, Xiao-lei M 1, Jing-ya C, et al. The pharmacokinetics and tissue distribution of honokiol and its metabolites in rats[J]. European journal of drug metabolism and pharmacokinetics, 2015: 1-8.(SCI 4区,IF1.680) 6. 苗潇磊, 王俊俊, 孟沫然, 陈勇*. 次乌头碱, 甘草苷单用与合用对大鼠肝脏CYP450酶mRNA表达与活性的影响[J]. 中华中医药杂志, 2016, 31(1): 313-316.(B类核心期刊) 7. 朱鹏1, 苗潇磊1, 陈勇*. 绿原酸, 隐绿原酸和新绿原酸在中性和碱性pH条件下的降解动力学[J]. 药学学报, 2016, 51(1): 122-126.(A类权威期刊)