一、学习和工作简历

2003.9-2007.7湖北大学化学生物学国家理科基地班理学学士

2007.9-2012.7复旦大学化学生物学专业理学博士生（硕博连读）

2012.8-2014.9美国约翰霍普金斯大学化学系博士后

2014.9-2015.10美国达特茅斯学院化学系博士后

2015.12-2016.10上海大学环境科学学院纳米化学与生物学研究所

2016.12-2017.7湖北大学生命科学学院讲师

2017.7-至今湖北大学生命科学学院副教授

二、承担科研项目情况

1.湖北省自然科学基金（201700963）

2.湖北大学专项启动经费

研究领域：化学生物学、金属蛋白酶作用机理、基因编辑酶的开发和利用、纳米生物医学

1.QiaoJie,JieQiao,LixinMa,JustineRoth,YaminLi,andYiLiu*,Kineticbasisfortheactivationofhumancyclooxygenase-2ratherthancyclooxygenase-1bynitricoxide,Org.Biomol.Chem.,(2018),16:765–770

2.YiLiu*,AonengCao*.EncapsulatingProteinsinNanoparticles:batchbybatchoronebyone.MethodsinEnzymology,(2017),590:1-31

3.YiLiu,JustineRoth*.Arevisedmechanismforhumancyclooxygenase-2.J.Bio.Chem.,(2016),291:948-958. 4.YiLiu,ArnabMukherjee,NadavNahumi,MehmetOzbil,DoreenBrown,AlfredoM.Angeles-Boza,DavidDooley*,RajeevPrabhakar*,andJustineRoth*.Experimentalandcomputationalevidenceofmetal-O2activationandrate-limitingproton-coupledelectrontransferinacopperamineoxidase.J.Phys.Chem.B.,(2013),117:218–229.

5.YiLiu,QingliWang,YaozhuWei,Ying-WuLin,WeiLi,Ji-HuSu,ZhengWang,YangTian,Zhong-XiangHuangandXiangshiTan*.Functionalconversionofnickel-containingmetalloproteinsviamoleculardesign:fromatruncatedacetyl-coenzymeAsynthasetoanickelsuperoxidedismutase.Chem.Commun.,(2013),49:1452-1454.

6.YiLiu,WeiLi,Yaozhu,Wei,YingdiJiangandXiangshiTan*EfficientpreparationandmetalspecificityoftheregulatoryproteinTroRfromthehumanpathogenTreponemapallidum.Metallomics,(2013),10:1448-1457

7.YiLiu,FengWang,PingweiLiandXiang-ShiTan*.Insightsintothemechanisticroleofthe[Fe4S4]cubaneintheA-cluster{[Fe4S4]-(SR)-[NipNid]}ofacetyl-coenzymeAsynthase.ChemBioChem,(2011),12:1417-1421.

8.YiLiu,Xiaofeizhu,FengWang,TianleiYing,PingweiLi,Zhong-xianHuangandXiangshiTan*.ProbingtheroleofthebridgingC509betweenthe[Fe4S4]cubaneandthe[NipNid]centerintheA-clusterofacetyl-coenzymeAsynthase.Chem.Commun.,(2010),47:1291-1293.

9.YiLiu,XiangshiTan*.ProgressinEPR-basedstudiesoncarbonmonoxidedehydrogenase/acetyl-coenzymeAsynthase.(Review)ChineseJournalofMagneticResonance,(2011),4:490-501.