药物合成，新型含氟化合物的设计、合成及生物活性评价，以及重要医药中间体的合成工艺研究。

1. Lin Li, Miao Li, Huiwei Chi, Jichun Yang, Zhinian Li, Changling Liu. Discovery of flufenoxystrobin: Novel fluorine-containing strobilurin fungicide and acaricide, Journal of Fluorine Chemistry. 185 (2016) 173–180 2. Changling Liu, Lin Li. Design, Synthesis，and Biological Activity of novel 4-（3，4-dimethoxyphenyl）-2-methylthiazole -5-carboxylic acide derivatives. Bioorganic & Medicinal Chemistry 12 (2004) 2825–2830 3. Changling Liu, Miao Li, Lin Li. Design, Synthesis and Fungicidal Activity of SYP-3343. Proceedings of 3rd International Symposium on Pesticide and Environmental Safety & 7th Interna-tional Workshop on Crop Protection Chemistry and Regulatory Harmonization) 2007 4. Meng Jing, Lin Li. Compound ICA-105574 prevents arrhythmias induced by cardiac delayed repolarization. European Journal of Pharmacology 718 (2013) 87–97 5. Miao Li, Changling Liu, Lin Li,,Design, Synthesis and Fungicidal Activity of SYP-3343 Proceedings of 3rd International Symposium on Pesticide and Environmental Safety & 7th Interna-tional Workshop on Crop Protection Chemistry and Regulatory Harmonization