主持项目（省部级以上）： 1. 国家自然科学基金青年基金 基于DESI-IMS技术的深海真菌抗耐药白色念珠菌活性成分靶向挖掘及其作用机制研究 2020.01-2022.12

海洋真菌来源活性次级代谢产物研究，包括海洋真菌来源新型抗肿瘤、抗真菌等活性功能分子的挖掘；复杂化合物结构鉴定，以及药理作用机制的研究

1. Liu Z, Chen Y, Chen S, et al. Aspterpenacids A and B, two sesterterpenoids from a mangrove endophytic fungus Aspergillus terreus H010 [J]. Organic Letters. 2016, 18(6): 1406-1409. 2. Liu Z, Chen Y, Chen S, et al. (+)- and (-)-Ascomlactone A: a pair of novel dimeric polyketides from a mangrove endophytic fungus Ascomycota sp. SK2YWS-L [J]. Organic & Biomolecular Chemistry. 2017, 15, 10276 - 10280. 3. Liu Z, Wang Q, Li S. et al. Polypropionate Derivatives with Mycobacterium tuberculosis Protein Tyrosine Phosphatase B Inhibitory Activities from the Deep-Sea-Derived Fungus Aspergillus fischeri FS452[J]. Journal of Natural Products, 2019, 82(12): 3440-3449. 4. Liu Z, Tan H, Chen K, et al. Rhizophols A and B, antioxidant and axially chiral benzophenones from the endophytic fungus Cytospora rhizophorae. Org. Biomol. Chem., 2019, 17:10009-10012. 5. Liu Z, Chen Y, Li S, et al. Bioactive Metabolites from the Deep-Sea-Derived Fungus Diaporthe longicolla FS429. Marine Drugs. 2020, 18:381-393.