教育经历 2013.09—2018.06 中山大学 化学学院 物理化学 博士 2009.09—2013.06 中山大学 化学学院 化学专业 本科 工作经历 2021.10—至今 广州医科大学 药学院 南山学者教授 2021.03—2021.08 中山大学孙逸仙纪念医院 放射科 助理研究员 2018.12—2020.12 中山大学孙逸仙纪念医院 放射科 博士后

1. 新型功能功能性生物分子杂交框架材料的设计 2. 可视化即时生命分析平台的构建与应用 3. 药物研发及递送用于疾病的治疗与实时监测

S. Huang, X. Kou, J. Shen, G. Chen*, G. Ouyang*. “Armor-Plating” Enzymes with Metal-Organic Frameworks (MOFs). Angew. Chem. Int. Ed. 2020, 59, 8786-8798 (IF=15.336, ESI高被引论文). S. Huang#, W. Zhu#, F. Zhang#, G. Chen, X. Kou, Y. Xie, G. Ouyang, J. Shen*. Silencing of Pyruvate Kinase M2 via a Metal–Organic Framework Based Theranostic Gene Nanomedicine for Triple-Negative Breast Cancer Therapy. ACS Appl. Mater. Interfaces 2021, 13, 56972−56987 (IF = 9.229). G. Chen#, S. Huang#, Y. Shen, X. Kou, X. Ma, Q. Tong, K. Ma, P. Wang, J. Shen, F. Zhu, G. Ouyang*. Proteins-powered hydrogen-bonded biohybrid framework. Chem 2021, 7, 2722-2742 (IF=22.804, hot paper). Z. Tang#, X. Li, L. Tong, H. Yang, J. Wu, X. Zhang, T. Song*, S. Huang*, F. Zhu, G. Chen*, G. Ouyang. A Biocatalytic Cascade in an Ultrastable Mesoporous Hydrogen-Bonded Organic Framework for Point-of-Care Biosensing. Angew. Chem. Int. Ed. 2021, 60, 23608-23613 (IF=15.336). X. Kou, L. Tong, S. Huang*, G. Chen*, F. Zhu*, G. Ouyang, Proteins-powered hydrogen-bonded biohybrid framework. 2021, TrAC Trends Anal. Chem. 2021, 136, 116182 (IF=12.296). G. Chen#, S. Huang#, X. Kou, F. Zhu, G. Ouyang*. Embedding Functional Biomacromolecules within Peptide-Directed Metal-Organic Framework (MOF) Nanoarchitectures Enables Activity Enhancement. Angew. Chem. Int. Ed. 2020, 59, 13947-13954 (IF=15.336, VIP paper). S. Huang, G. Chen, R. Ye, X. Kou, R. Zhang, J. Shen*, G. Ouyang*. Iron-mineralization-induced mesoporous metalorganic frameworks enable high-efficiency synergistic catalysis of natural/nanomimic enzymes. ACS Appl. Mater. Interfaces 2020, 12, 51, 57343-57351. (IF= 9.229). X. Kou, L. Tong, Y. Shen, W. Zhu, L. Yin, S. Huang*, F. Zhu*, G. Chen*, G. Ouyang. Smartphone-assisted robust enzymes@MOFs-based paper biosensor for point-of-care detection, Biosens. Bioelectron. 2020, 156, 112095 (IF=10.618).