高瑜 照片

高瑜

教授 博导

所属大学: 福州大学

所属学院: 化学学院

邮箱:
hellogaoyu@126.com

个人主页:
https://chem.fzu.edu.cn/info/1194/8432.htm

个人简介

2005.09–2010.07 中国科学院上海药物研究所 博士 专业:药剂学 2010.07–2011.10 中国科学院上海药物研究所 助理研究员 2013.03–2019.07 福州大学 副教授、教授 2017.09–2018.9 华盛顿大学药学院 访问学者

研究领域

主要从事创新药物制剂的研究,以提高药物的有效性、降低毒副作用。主要学术成绩涵盖药物新材料、新技术和新工艺的应用基础研究

近期论文

Ziying Li, Yilin Zheng, Huifang Shi, Huanzhang Xie, Ya Yang, Fangyin Zhu, Lingjie Ke, Haijun Chen, Yu Gao*. Convenient Tuning of the Elasticity of Self-assembled Nano-sized Triterpenoid to Regulate Their Biological Activities. ACS Applied Materials & Interfaces. 2021, 13, 37, 44065–44078. (IF = 9.229) Peixia Zhang, Lu Zhang, Jun Wang, Lisheng Zhu, Ziying Li, Haijun Chen, and Yu Gao*. An Intelligent Hypoxia-Relieving Chitosan-based Nanoplatform for Enhanced Targeted Chemo-Sonodynamic Combination Therapy on Lung Cancer. Carbohydrate Polymers. Volume 274, 15 November 2021, 118655 (IF = 9.381) Yilin Zheng#, Jinxiang Ye#, Ziying Li, Haijun Chen*, Yu Gao*. Recent Progress in Sono-photodynamic Cancer Therapy: From Developed New Sensitizers to Nanotechnology-Based Efficacy Enhancing Strategies. Acta Pharmaceutica Sinica B. 2021, 11(8): 2197-2219 . (IF = 11.413) Ziying Li, Lisheng Zhu, Weiqun Liu, Yilin Zheng, Xudong Li, Jinxiang Ye, Beifei Li, Haijun Chen, Yu Gao*. Near-infrared/pH dual-responsive nanocomplexes for targeted imaging and chemo/gene/photothermal tri-therapies of non-small cell lung cancer. Acta Biomaterialia 2020, Volume 107, 15 April 2020, Pages 242-259. (IF = 7.242). Yingying Zhang1, Lu Zhang1, Xiaowen Lin, Lingjie Ke, Bifei Li, Liang Xu, Tingting Lv, Ziying Li, Haijun Chen and Yu Gao*. Dual-responsive nanosystem for precise molecular subtyping and resistant reversal of EGFR targeted therapy, Chemical Engineering Journal, 372 (2019) 483–495. (IF = 10.317) Tingting Lv, Ziying Li, Liang Xu, Yingying Zhang, Haijun Chen, Yu Gao*. Chloroquine in combination with aptamer-modified nanocomplexes for tumor vessel normalization and efficient erlotinib/Survivin shRNA co-delivery to overcome drug resistance in EGFR-mutated non-small cell lung cancer. Acta Biomater. 76 (2018) 257–274. (IF = 6.383) Fengqiao Li, Hao Mei, Yu Gao*, Xiaodong Xie, Huifang Nie, Tao Li, Huijuan Zhang, Lee Jia*. Co-delivery of oxygen and erlotinib by aptamer-modified liposomal complexes to reverse hypoxia-induced drug resistance in lung cancer. Biomaterials 145 (2017) 56-71. (IF = 8.402) Yingying Zhang, Tingting Lv, Huijuan Zhang, Xiaodong Xie, Ziying Li, Haijun Chen, Yu Gao*. Folate and heptamethine cyanine modified chitosan-based nanotheranostics for tumor targeted near infrared fluorescence imaging and photodynamic therapy. Biomacromolecules. 18 (2017) 2146-2160. (IF = 5.246)