2003年6月在南京大学获分析化学博士学位，2003年8月至2005年8月分别为德国Potsdam大学和加拿大Lakehead University博士后，2005年被聘为东南大学化学化工学院教授。从事生物界面、生物组装和电化学分析方面的教学和科研工作，主持包括国家重大仪器专项（基金委）、国家重点研发计划（科技部）、国家自然科学基金重点/面上、江苏省自然科学基金重点和江苏省工业支撑项目等项目，并开展纳米生物探针、纳米增强高分子材料和纳米钛管氢敏传感器的产业化研究。共发表SCI收录论文260余篇，被SCI刊物他人引用11000余次，获授权发明专利23件，个人H-index为56，分别为五部专著编写5章。获2010年、2015年教育部自然科学奖一等奖，2011年度“全国化工优秀科技工作者”称号。兼任江苏省富碳材料与器件工程实验室主任、中国分析测试协会理事、中国分析测试协会高校分析测试分会常务理事、中国仪器仪表学会分析仪器分会电分析化学专业委员会委员、中国有机电化学与工业行业联合会常务理事、江苏省富碳材料与器件工程专业委员会主任委员、江苏省化学化工学会理事、江苏省分析测试协会常务理事、江苏省分析测试协会高校分会副理事长，并担任Analytica Chimica Acta编辑（2020-）、World Journal of Biological Chemistry 副主编（2016-2018）。

科学仪器专项：发展单细胞活性分子时空分辨分析系统，实现单细胞生物活性分子如蛋白、核酸、双氧水、多巴胺、抗坏血酸、小RNA等的高时空分辨分析； 多级次纳米结构构筑与二氧化碳还原：利用多孔材料组装单/多生物分子（酶或菌类）和电子供（受）体，构建多酶、多步骤多功能耦合CO2生物还原体系； 食品安全快检方法学和试剂盒研制； 外泌体分离、检测与生物应用：构筑微流控芯片，实现外泌体高效捕获与多生物信息获取，探索极端环境外泌体特征及其生物调节的分子基础； 多模态多物理因子干预诊疗一体化纳米生物探针

Zhaoyan Tian, Yafeng Wu,* Fengying Shao, Dezhi Tang, Xiang Qin, Chenchen Wang, Songqin Liu*, Electrofluorochromic Imaging Analysis of Glycan Expression on Living Single Cell with Bipolar Electrode Arrays. Analytical Chemistry 2021, 93, 5114−5122 Yafeng Wu, Zixuan Chen, Zhipeng Yao, Kaige Zhao, Fengying Shao, Juan Su, and Songqin Liu*, Black Phosphorus Quantum Dots Encapsulated Biodegradable Hollow Mesoporous MnO: Dual-Modality Cancer Imaging and Synergistic Chemo-Phototherapy. Advanced Functional Materials 2021, 2104643. Fengying Shao, Yafeng Wu*, Zhaoyan Tian, Songqin Liu. Biomimetic nanoreactor for targeted cancer starvation therapy and cascade amplificated chemotherapy. Biomaterials 2021, 274, 120869 Kan Wang, Fen Zhang, Yuanqing Wei, Wei Wei, Ling Jiang,* Zewen Liu,* and Songqin Liu*. In Situ Imaging of Cellular Reactive Oxygen Species and Caspase 3 Activity Using a Multifunctional Theranostic Probe for Cancer Diagnosis and Therapy. Analytical Chemistry 2021, 93, 7870-7878 Sisi Zhou, Tao Hu, Gaohua Han, Yafeng Wu,* Xin Hua, Juan Su, Weiwei Jin, Yiping Mou, Xiaozhou Mou, Quan Li, and Songqin Liu. Accurate Cancer Diagnosis and Stage Monitoring Enabled by Comprehensive Profiling of Different Types of Exosomal Biomarkers: Surface Proteins and miRNAs. Small 2020, 16, 2004492 Yafeng Wu, Yaqiong Gao, Juan Su, Zixuan Chen and Songqin Liu*, In situ detection of intracellular tissue transglutaminase based on aggregation-induced emission. Chemical Communications 2020, 56, 9008-9011 Fen Zhang, Wenming Liu,* Sisi Zhou, Ling Jiang, Kan Wang, Yuanqing Wei, Anran Liu, Wei Wei, and Songqin Liu*, Investigation of Environmental Pollutant-Induced Lung Inflammation and Injury in a 3D Coculture-Based Microfluidic Pulmonary Alveolus System. Analytical Chemistry 2020, 92 (10), 7200-7208 Sisi Zhou, Tao Hu, Fen Zhang, Dezhi Tang, Dake Li,* Jian Cao, Wei Wei, Yafeng Wu,* and Songqin Liu*, Integrated Microfluidic Device for Accurate Extracellular Vesicle Quantification and Protein Markers Analysis Directly from Human Whole Blood. Analytical Chemistry 2020, 92, 1, 1574-1581 Juan Su, Fubing Wu, Hongping Xia,* Yafeng Wu * and Songqin Liu *, Accurate cancer cell identification and microRNA silencing induced therapy using tailored DNA tetrahedron nanostructures. Chemical Science 2020, 11, 80 Cheng Zheng, Xueying Qiu, Jianyu Han,* Yafeng Wu,* and Songqin Liu, Zero-Dimensional-g-CNQD-Coordinated Two-Dimensional Porphyrin MOF Hybrids for Boosting Photocatalytic CO2 Reduction. ACS Applied Materials and Interfaces 2019, 11, 42243-42249 Fengying Shao, Li Mi,* Zhaoyan Tian, Cheng Zheng, Yuanjian Zhang, Quan Li, and Songqin Liu*, Promoting Photodegradation Efficiency via a Heterojunction Photocatalyst Combining with Oxygen Direct and Fast Diffusion from the Gas Phase to Active Catalytic Sites. ACS Applied Materials and Interfaces 2019, 11, 44922-44930 Li Mi, Jing Sui, Yafeng Wu,* Geyu Liang, Yuanjian Zhang, Yuepu Pu, Ye Tian,* Songqin Liu,* and Lei Jiang, Bioinspired in Vitro Lung Airway Model for Inflammatory Analysis via Hydrophobic Nanochannel Membrane with Joint Three-Phase Interface. Analytical Chemistry 2019, 91, 15804-15810 Yafeng Wu, Fen Zhang, Kan Wang, Peicheng Luo, Yuanqing Wei,* and Songqin Liu*, Activatable Fluorescence Imaging and Targeted Drug Delivery via Extracellular Vesicle-Like Porous Coordination Polymer Nanoparticles. Analytical Chemistry 2019, 91, 14036-14042 Yuanqing Wei, Hongping Xia, Fen Zhang, Kan Wang, Peicheng Luo, Yafeng Wu,* and Songqin Liu. Theranostic Nanoprobe Mediated Simultaneous Monitoring and Inhibition of P Glycoprotein Potentiating Multidrug-Resistant Cancer Therapy. Analytical Chemistry 2019, 91, 11200-11208 Zhaoyan Tian, Li Mi, Yafeng Wu,* Fengying Shao, Mingqiang Zou, Zhenxian Zhou, Songqin Liu*, Visual Electrofluorochromic Detection of Cancer Cell Surface Glycoprotein on a Closed Bipolar Electrode Chip. Analytical Chemistry 2019, 91, 7902-7910 Kaige Zhao, Min Tang, Huaisheng Wang, Zhenxian Zhou, Yafeng Wu*, Songqin Liu,* Simultaneous Detection of Three Biomarkers Related to Acute Myocardial Infarction Based on Immunosensing Biochip. Biosensors and Bioelectronics 2019, 126, 767-772 Fen Zhang, Chang Tian, Wenming Liu,* Kan Wang, Yuanqing Wei, Huaisheng Wang, Jinyi Wang,* and Songqin Liu*, Determination of Benzopyrene-Induced Lung Inflammatory and Cytotoxic Injury in a Chemical Gradient-Integrated Microfluidic Bronchial Epithelium System. ACS Sensors 2018, 3, 2716-272 Ling Jiang, Kan Wang, Fen Zhang, Yuanjian Zhang, Huaisheng Wang* and Songqin Liu*, Enhanced Metabolic Activity of Cytochrome P450 via Carbon Nanocage-Based Photochemical Bionanoreactor. ACS Applied Materials & Interfaces 2018, 10, 41956-41961 Kan Wang, Ling Jiang, Fen Zhang, Yuanqing Wei, Kang Wang,* Huaisheng Wang, Zhengjian Qi, and Songqin Liu*, Strategy for In Situ Imaging of Cellular Alkaline Phosphatase Activity Using Gold Nanoflower Probe and Localized Surface Plasmon Resonance Technique. Analytical Chemistry 2018, 90, 14056-14062 Yuewu Zhao, Ling Jiang, Li Shangguan, Li Mi, Anran Liu, Songqin Liu*, Synthesis of porphyrin-based two-dimensional metalorganic framework nanodisk with small size and less layers. Journal of Materials Chemistry A 2018, 6, 2828-2833