宋锋玲
教授 博导
个人简介
1995年09月至1999年07月大连理工大学应用化学专业,学士学位 1999年09月至2005年10月大连理工大学应用化学专业,博士学位 2006年01月至2006年11月美国Wayne State University化学系, 有机化学博士后 2006年12月至2009年11月美国University of Pittsburgh化学系, 有机化学博士后 2012年07月至2012年11月美国Washington University in St Louis医学院, 访问学者 2009年12月至2012年12月大连理工大学精细化工国家重点实验室副教授。 2012年12月至今 大连理工大学精细化工国家重点实验室教授 2014年06月至今 大连理工大学精细化工国家重点实验室博士生导师
研究领域
有机荧光染料的光物理现象,以及有机荧光染料的生物影像和生物靶标检测的应用 纳米荧光粒子的制备,以及其在纳米医学领域的应用
近期论文
An, Jing; Tang, Shanliang; Hong, Gaobo; Chen, Wenlong; Chen, Miaomiao; Lv, Shibo; Song, Jitao Dapeng, Liu; Li, Zhiliang; Peng, Xiaojun; Song, Fengling;* Zheng, Wen-heng.* An Unexpected Strategy to Alleviate Hypoxia Limitation of Photodynamic Therapy by Biotination of Photosensitizers. Nature Communications, 2022, 13, 2225. Feng, Erting; Jiao, Long; Tang, Shanliang; Chen, Miaomiao; Lv, Shibo; Dapeng, Liu; Song, Jitao; Peng, Xiaojun; Song, Fengling;* Anti-Photobleaching Cyanine-Based Nanoparticles with Simultaneous PET and ACQ Effects for Improved Tumor Photothermal Therapy. Chemical Engineering Journal, 2022, 432, 134355. Feng, Erting; Liu, Yuhan; Lv, Shibo; Dapeng, Liu;* Huang, Shuheng; Li, Zhiliang; Song, Fengling.* Fine-Tuning Cu (II)-Induced Self-Assembly of Hydrophilic Cyanine Dyes for Enhanced Tumor Photothermal Therapy. Adv. Funct. Mater., 2022, 32, 2209258 Jiao, Long; Liu, Yongzhuo; Zhang, Xiaoye; Hong, Gaobo; Zheng, Jing; Cui, Jingnan; Peng, Xiaojun Song, Fengling.* Constructing a Local Hydrophobic Cage in Dye-Doped Fluorescent Silica Nanoparticles to Enhance the Photophysical Properties. ACS Central Science 2020, 6,747-759. Xiong, Xiaoqing; Song, Fengling;* Wang, Jingyun; Zhang, Yukang; Xue, Yingying; Sun, Liangliang; Jiang, Na; Gao, Pan; Tian, Lu; Peng, Xiaojun. Thermally Activated Delayed Fluorescence of Fluorescein Derivative for Time-Resolved and Confocal Fluorescence Imaging. J. Am. Chem. Soc. 2014, 136, 9590−9597. Song, Fengling; Watanabe, Shuji; Floreancig, Paul E.; Koide, Kazunori.* Oxidation-resistant fluorogenic probe for mercury based on alkyne oxymercuration. J. Am. Chem. Soc. 2008, 130, 16460–16461. Song, Fengling; Garner, Amanda L; Koide, Kazunori.* A highly sensitive fluorescent sensor for palladium based on the allylic oxidative insertion mechanism. J. Am. Chem. Soc. 2007, 129, 12354–12355. Peng, Xiaojun;* Song, Fengling; Lu, Erhu; Wang, Yanan; Zhou, Wei; Fan, Jiangli; Gao, Yunling. Heptamethine cyanine dyes with a large stokes shift and strong fluorescence: A paradigm for excited-state intramolecular charge transfer. J. Am. Chem. Soc. 2005, 127, 4170-4171. Wu, Yingnan; Zhao, Yanliang; Hou, Haoran; Hong, Gaobo; Guo, Hanhui; Zhang, Ruiling; Chen, Wenlong; Tian, Jiarui; Lv, Shibo; Wang, Honglei; Wang, Meishan;* Wu, Chenyu;* Song, Fengling.* Oxygen-Insensitive Delayed Fluorescence Based on Singlet Manifold. Advanced Optical Materials, 2022, doi.org/10.1002/adom.202202413 Sun, Han; Guo, Ruihua; Guo, Yanhui; Song, Jitao; Li, Zhiliang;* Song, Fengling.* Boosting Type‑I and Type-II ROS Production of Water-Soluble Porphyrin for Efficient Hypoxic Tumor Therapy. Mol. Pharmaceutics, 2022, 19, doi.org/10.1021/acs.molpharmaceut.2c00822 Lv, Fangyuan; Fan, Xiaoxue; Liu, Dapeng;* Song, Fengling;* Photothermal agents based on small organic fluorophores with intramolecular motion. Acta Biomaterialia 2022, 149, 16-29. Feng, Erting; Liu, Yuhan; Lv, Shibo; Dapeng, Liu;* Huang, Shuheng; Li, Zhiliang; Song, Fengling.* Fine-Tuning Cu (II)-Induced Self-Assembly of Hydrophilic Cyanine Dyes for Enhanced Tumor Photothermal Therapy. Adv. Funct. Mater., 2022,32, 2209258. Lv, Shibo; Liu, Yuhan; Zhao, Yanliang; Fan, Xiaoxue; Lv, Fangyuan; Feng, Erting; Dapeng, Liu;* Song, Fengling.* Rational design of a small organic photosensitizer for NIR-I imaging-guided synergistic photodynamic and photothermal therapy. Biomater. Sci., 2022, 10, 4785-4795. Jin, Lin; Miao, Yuyang; Dapeng, Liu;* Song, Fengling.*Fe/Mn-Porphyrin Coordination Polymer Nanoparticles for Magnetic Resonance Imaging (MRI) Guided-Combination Therapy between Photodynamic Therapy and Chemodynamic Therapy. ChemistrySelect, 2022, 7, e202104366. Guo, Yanhui; Huang, Shuheng; Sun, Han; Wang, Zhe; Shao, Yutong; Li, Lukun; Li, Zhiliang;* Song, Fengling.* Tuning the aqueous self-assembly of porphyrins by varying the number of cationic side chains. J. Mater. Chem. B, 2022, 105, 5968–5975. Sun, Jinghan; Feng, Erting; Shao, Yutong; Lv, Fangyuan; Wu, Yingnan; Tian, Jiarui; Sun, Han; Song, Fengling.* A selenium-substituted heptamethine cyanine photosensitizer for near-infrared photodynamic therapy. ChemBioChem, 2022, e202200421. Wang, Donghui; Hou, Haoran; Chen, Wenlong; Wu, Yingnan; Peng, Xiaojun; Song, Fengling.* A turn-on fluorescent probe for palladium(II) detection with a large Stokes shift and lysosomes-targeting ability. Tetrahedron Letters, 2022, 102,153932. Chen, Miaomiao; Zhao, Shuju; Zhu, Jialong; Feng, Erting; Lv, Fangyuan; Chen, Wenlong; Lv, Shibo; Wu, Yingnan; Peng, Xiaojun; Song, Fengling.* Open-Source and Reduced-Expenditure Nanosystem with ROS Self-Amplification and Glutathione Depletion for Simultaneous Augmented Chemodynamic/Photodynamic Therapy. ACS Applied Materials & Interfaces 2022, 14, 20682-20692. An, Jing; Tang, Shanliang; Feng, Erting; Tian, Mingyu; Chen, Wenlong; Chen, Miaomiao; Hong, Gaobo; Peng, Xiaojun; Song, Fengling.* Naphthofluorescein-Based Organic Nanoparticles with Superior Stability for Near-Infrared Photothermal Therapy. Nanoscale, 2022, 14, 10051–10059. An, Jing; Tang, Shanliang; Hong, Gaobo; Chen, Wenlong; Chen, Miaomiao; Lv, Shibo; Song, Jitao Dapeng, Liu; Li, Zhiliang; Peng, Xiaojun; Song, Fengling;* Zheng, Wen-heng.* An Unexpected Strategy to Alleviate Hypoxia Limitation of Photodynamic Therapy by Biotination of Photosensitizers. Nature Communications, 2022, 13, 2225. Tian, Mingyu; Chen, Wenlong; Wu, Yingnan; An, Jing; Hong, Gaobo; Chen, Miaomiao; Song, Fengling;* Zheng, Wen-heng;* Peng, Xiaojun. Liposome-Based Nanoencapsulation of a Mitochondria-Stapling Photosensitizer for Efficient Photodynamic Therapy. ACS Applied Materials & Interfaces 2022, 14, 12050-12058. Zhao, Yanliang; Wu,Yingnan; Chen, Wenlong; Zhang, Ruiling; Hong, Gaobo; Tian, Jiarui; Wang, Honglei; Zheng, Daoyuan; Zhou, Wu, Chenyu; Jiang, Xiao; Huo, Xinming; Sun, Lei;*; Deng, Weiqiao; Han, Keli; Song, Fengling.* The Second Excited Triplet−State Facilitates TADF and Triplet−Triplet Annihilation Photon Upconversion via a Thermally Activated Reverse Internal Conversion. Advanced Optical Materials, 2022,10, 2102275. Feng, Erting; Jiao, Long; Tang, Shanliang; Chen, Miaomiao; Lv, Shibo; Dapeng, Liu; Song, Jitao; Peng, Xiaojun; Song, Fengling.* Anti-Photobleaching Cyanine-Based Nanoparticles with Simultaneous PET and ACQ Effects for Improved Tumor Photothermal Therapy. Chemical Engineering Journal, 2022, 432, 134355. Chen, Shuang; Liu, Yongzhuo; Liang, Ri; Hong, Gaobo; An, Jing; Peng, Xiaojun; Zheng, Wen-heng;* Song, Fengling.* Self-assembly of amphiphilic peptides to construct activatable nanophotosensitizers for theranostic photodynamic therapy. Chinese Chemical Letters, 2021, 32, 3903-3906. Tang, Shanliang; An, Jing; Song, Fengling;* Lv, Meiheng; Han, Keli; Peng, Xiaojun. Extending the legible time of light-responsive rewritable paper with a tunable photochromic diarylethene molecule. ACS Applied Materials & Interfaces 2021, 13, 51441-51425. Chen, Miaomiao; Song, Jitao;* Zhu, Jialong; Hong, Gaobo; An, Jing; Feng, Erting; Peng, Xiaojun; Song, Fengling.* A Dual-Nanozyme-Catalyzed Cascade Reactor for Enhanced Photodynamic Oncotherapy against Tumor Hypoxia. Adv. Healthcare Mater., 2021, 10, 2101049. Shao, Yutong; Song, Jitao;* Li, Xiaorong; Ren, Guoqing; Song, Fengling;* Synthesis of Noble Metal M@YSiO 2 Yolk−Shell Nanoparticles with Thin Organic/Inorganic Hybrid Outer Shells via an Aqueous Medium Phase. Langmuir 2021, 37, 7237-7245. Liu, Yuhan; Chen, Miaomiao; Zhao,Yanliang; Lv, Shibo; Zheng, Daoyuan; Dapeng, Liu;* Song, Fengling;* A Novel D-A-D Photosensitizer for Efficient NIR Imaging and Photodynamic Therapy. ChemBioChem 2021, 22, 2161-2167. Lv, Fangyuan; Liu, Dapeng;* Zheng, Wen-heng; Zhao,Yanliang; Song, Fengling;* BOPHY-Based Aggregation-Induced-Emission Nanoparticle Photosensitizers for Photodynamic Therapy. ACS Appl. Nano Mater. 2021, 4, 6012-6019. Li, Xiaorong; Shao, Yutong; Lv, Shibo; Tian, Jiarui; Zheng, Daoyuan; Song, Jitao;* Song, Fengling;* Au@mSiO 2 core–shell nanoparticles loaded with fluorescent dyes: synthesis and application for imaging performance. Dalton Trans., 2021, 50, 5624-5631. Miao, Yuyang; Lv, Shibo; Zheng, Daoyuan; Liu, Yuhan; Liu, Dapeng;* Song, Fengling;* Porphyrin-based metal coordination polymers with self-assembly pathway-dependent properties for photodynamic and photothermal therapy. Biomater. Sci., 2021, 9, 2533-2541. Chen, Miaomiao; Liu, Dapeng; Liu, Fusheng; Wu,Yingnan; Peng, Xiaojun; Song, Fengling.* Recent advances of redox-responsive nanoplatforms for tumor theranostics. Journal of Controlled Release, 2021, 332,269-284. Jin, Lin; Lv, Shibo; Miao, Yuyang; Liu,Dapeng*; Song, Fengling;* Recent Development of Porous Porphyrin-based Nanomaterials for Photocatalysis. ChemCatChem, 2021, 13, 140—152. Lv, Shibo; Miao, Yuyang; Zheng, Daoyang; Li, Xiaoju; Liu,Dapeng*; Song, Fengling;* Self-Assembled Platinum Supramolecular Metallacycles Based on a Novel TADF Photosensitizer for Efficient Cancer Photochemotherapy. Mol. Pharmaceutics, 2021, 18, 1229−1237 Liu, Yuhan; Lv, Shibo; Liu,Dapeng; Song, Fengling;* Recent development of amorphous metal coordination polymers for cancer therapy. Acta Biomaterialia, 2020, 116, 16-31. Lv, Shibo; Miao, Yuyang; Liu,Dapeng*; Song, Fengling.* Recent Development of Photothermal Agents (PTAs) Based on Small Organic Molecular Dyes. ChemBioChem, 2020, 21, 2098—2110. Ying, Huiyi; Wu,Yingnan; Peng, Xiaojun; Song, Fengling.* A turn-on TADF chemosensor for sulfite with a microsecond-scale luminescence lifetime. Chemical Communications, 2020, 56, 10549—10551. Wu,Yingnan; Zhao, Yanliang; Zhou, Panwang; Zheng, Daoyuan; Wang, Honglei; Tang, Shanliang; Tian, Jiarui; Yang, Songqiu; Deng, Weiqiao; Han, Keli; Song, Fengling.* Enhancing Intersystem Crossing to Achieve Thermally Activated Delayed Fluorescence in a Water-Soluble Fluorescein Derivative with a Flexible Propenyl Group. J. Phys. Chem. Lett. 2020, 11, 5692–5698. Jiao, Long; Liu, Yongzhuo; Zhang, Xiaoye; Hong, Gaobo; Zheng, Jing; Cui, Jingnan; Peng, Xiaojun Song, Fengling.* Constructing a Local Hydrophobic Cage in Dye-Doped Fluorescent Silica Nanoparticles to Enhance the Photophysical Properties. ACS Central Science 2020, 6,747-759. Zheng, Jing; Liu, Yongzhuo; Song, Fengling;* Jiao, Long; Wu,Yingnan; Peng, Xiaojun. A nitroreductase-activatable near-infrared theranostic photosensitizer for photodynamic therapy under mild hypoxia. Chemical Communications, 2020, 56, 5819-5822. Wu,Yingnan; Jiao, Long; Song, Fengling;* Chen, Miaomiao; Liu, Dapeng;* Yang, Wei; Yuming, Sun; Hong, Gaobo; Wu,Yingnan; Liu, lingge; Peng, Xiaojun. Achieving Long-lived thermally activated delayed fluorescence in the atmospheric aqueous environment by nano-encapsulation. Chemical Communications, 2019, 55, 14522--14525 Chen, Wenlong; Song, Fengling.* Thermally activated delayed fluorescence molecules and their new applications aside from OLEDs. Chinese Chemical Letters, 2019, 30, 1717-1730. Liu, Zhiwei; Shi, Wenbo; Hong, Gaobo; Chen,Wenlong; Song, Bo; Peng, Xiaojun; Xiong, Xiaoqing;* Song, Fengling.* A dual-targeted theranostic photosensitizer based on a TADF fluorescein derivative. Journal of Controlled Release 2019, 310, 1−10. Jiao, Long; Zhang, Xiaoye; Cui, Jingnan; Peng, Xiaojun Song, Fengling.* Three-in-one Functional Silica Nanocarrier with Singlet Oxygen Generation, Storage/release and Self-monitoring for Enhanced Fractional Photodynamic Therapy. ACS Applied Materials & Interfaces 2019, 11, 27250-27257. Liu, Zhiwei; Song, Fengling;* Shi, Wenbo; Gurzadyan, Gagik; Yin, Huiyi; Song, Bo; Liang, Ri; Peng, Xiaojun. Nitroreductase-activatable theranostic molecules with high PDT efficiency under mild hypoxia based on a TADF fluorescein derivative. ACS Applied Materials & Interfaces 2019, 11, 15426−15435. Chen, Wenlong; Song, Fengling;* Tang, Shanliang; Hong, Gaobo; Wu,Yingnan; Peng, Xiaojun. Red-to-blue photon up-conversion with high efficiency based on a TADF fluorescein derivative. Chemical Communications, 2019, 55, 4375 - 4378 Tang, Shanliang; Song, Fengling;* Lu, Meiheng; Han, Keli; Peng, Xiaojun. Rational design of a visible-light photochromic diarylethene: a simple strategy by extending conjugation with electron donating groups. SCIENCE CHINA Chemistry 2019, 62, 451-459. Jiao, Long; Song, Fengling;* Cui, Jingnan; Peng, Xiaojun. A near infrared heptamethine aminocyanine dye with a long-living excited triplet state for photodynamic therapy. Chemical Communications, 2018, 54, 9198 – 9201. Liu, Zhiwei; Song, Fengling;* Song, Bo; Jiao, Long; An, Jing; Yuan, Jingli; Peng, Xiaojun. A FRET chemosensor for hypochlorite with large Stokes Shifts and long-lifetime emissions. Sensors & Actuators: B. Chemical 2018, 262,958-965. An, Jing; Wu, Yingnan; Lu, Meiheng; Han, Keli; Song, Fengling;* Peng, Xiaojun. Long-Wavelength Chromophores with Thermally Activated Delayed Fluorescence Based on Fluorescein Derivatives. Journal of Photonics for Energy, 2018, 8(3), 032103.