Ph.D., University of Goettingen (Germany) 2002 - 2006 M.Sc., University of Goettingen (Germany) 2002 B.Sc., University of Malaya (Malaysia) 2000

Transcriptional maintenance of pancreatic acinar identity, differentiation, and homeostasis by PTF1A. Molecular and Cellular Biology. 2016 Academic Article GET IT Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing β-cells to a δ-like fate and reveals a facultative proliferative capacity in aged β-cells. Development. 2015 Academic Article GET IT Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3. Frontiers in Neural Circuits. 2015 Academic Article GET IT The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma. eLife. 2015 Academic Article GET IT Pancreas development in humans. Current Opinion in Endocrinology, Diabetes and Obesity. 2014 Review GET IT Identification and manipulation of biliary metaplasia in pancreatic tumors. Gastroenterology. 2014 Academic Article GET IT Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice. Nature Biotechnology. 2014 Academic Article GET IT Vascular endothelial growth factor-a and islet vascularization are necessary in developing, but not adult, pancreatic islets. Diabetes. 2013 Academic Article GET IT The Purkinje Neuron Acts as a Central Regulator of Spatially and Functionally Distinct Cerebellar Precursors. Developmental Cell. 2013 Academic Article GET IT Spatiotemporal patterns of multipotentiality in Ptf1aexpressing cells during pancreas organogenesis and injuryinduced facultative restoration. Development. 2013 Academic Article GET IT Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma. Cancer Cell. 2012 Academic Article GET IT Ongoing Notch signaling maintains phenotypic fidelity in the adult exocrine pancreas. Developmental Biology. 2012 Academic Article GET IT Isolation of mouse pancreatic alpha, beta, duct and acinar populations with cell surface markers. Molecular and Cellular Endocrinology. 2011 Academic Article GET IT Pancreas organogenesis: From bud to plexus to gland. Developmental Dynamics. 2011 Review GET IT Generation of transgenic frogs. Methods in Molecular Biology. 2009 Academic Article GET IT Molecular Genetics of Liver and Pancreas Development. 2008 Chapter GET IT Retinoic acid-mediated patterning of the pre-pancreatic endoderm in Xenopus operates via direct and indirect mechanisms. Mechanisms of Development. 2007 Academic Article GET IT Retinoic acid signaling is essential for pancreas development and promotes endocrine at the expense of exocrine cell differentiation in Xenopus. Developmental Biology. 2004 Academic Article GET IT