Grove, Tijana Z.
Assistant Professor
所属大学: Virginia Polytechnic Institute and State University
所属学院: College of Science
个人简介
Undergraduate Studies, University of Belgrade, 1999 Ph.D., Iowa State University, 2004 Postdoctoral Fellow, Yale University, 2006-2011 Assistant Professor of Chemistry, Virginia Tech, 2011-present
研究领域
Biomaterials/Chemical Biology/Bioanalytical
Many fundamental, yet complex, biological functions are carried out by molecular machineries composed of biopolymers, especially proteins and peptides. Recent advancements in protein and peptide engineering tools have facilitated scientific progress towards a new class of soft materials that merge unique properties of bio- and synthetic polymers.
The Grove lab focuses on design and synthesis of proteins and peptides for a broad variety of applications including assembly of nanostructured materials with tunable morphology and function, biosensing, and drug delivery. Our work is highly interdisciplinary and students will receive training in several areas of chemistry, structural biology, and materials science.
Current projects include:
Synthesis, assembly, and characterization of protein-polymer conjugates Biotemplating of inorganic nanoparticles for optical sensors Design of capture agents for glycan sensing Design of theranostic nanoparticles
近期论文
Tijana Z. Grove, Chinedum O. Osuji, Jason D. Forster, Eric R. Dufresne, Lynne Regan; "Stimuli-Responsive Smart Gels Realized via Modular Protein Design" J. Am. Chem. Soc. 2010, 132, 14024-14026. Tijana Z. Grove, Michael Hands, Lynne Regan; "Creating novel proteins by combining design and selection" Protein Eng. Des. Sel. 2010, 23, 449-55.
Tijana Z. Grove, Aitziber L. Cortajarena, Lynne Regan; "Ligand binding by repeat proteins: natural and designed" Curr. Opin. Struct. Biol. 2008, 18, 507-15.