Non-equilibrium condensed matter physics with special attention to the modeling of nanostructures systems and local probing techniques. Particular focus is directed on impurity scattering in two-dimensional systems, where the impurities possess bosonic (vibrational, spin, ...) degrees of freedom which give rise to inelastic scattering processes. Interactions between local defects adsorbed onto surface of modern materials e.g. superconductors, graphene, topological insulators, strongly spin-orbit coupled surfaces, and hidden order materials. At the moment my devotion is set to chiral induced spin selectivity, where spatial and spin degrees of freedom cooperate with electron correlations and vibrations to generate a macroscopically measurable spin asymmetry in the charge current.