The chemical synthesis of functional organic molecules underpins many key advances in human medicine, crop protection, biotechnology, and material science. Hence, the development of efficient, cost-effective routes to carbon-based molecules is an important, contemporary scientific challenge. Work in the Shipman Group is focused on the development of new methods for the construction of organic compounds alongside a variety of application-driven projects. We are especially interested in new uses of strained (3- and 4- membered) heterocycles.

Synthesis and structure of oxetane containing tripeptide motifs N. H. Powell, G. J. Clarkson, R. Notman, P. Raubo, N. G. Martin, M. Shipman, Chem. Commun., 2014, 8797. Asymmetric Synthesis of 2-Substituted Oxetan-3-ones via Metallated SAMP/RAMP Hydrazones J. V. Geden, B. O. Beasley, G. J. Clarkson, M. Shipman, J. Org. Chem., 2013, 78, 12243–12250. Photochemical control of molecular motion associated with pyramidal inversion A. J. Hough, I. Prokes, J. H. R. Tucker, M. Shipman, T. R. Walsh, Chem. Commun., 2013, 6683-6685. Palladium-Catalyzed Multicomponent Synthesis of 2-Aryl-2-Imidazolines from Aryl Halides and Diamines J. V. Geden, A. K. Pancholi, M. Shipman, J. Org. Chem., 2013, 78, 4158. Ultra-High Voltage Multijunction Organic Solar Cells for Low-Power Electronic Applications P. Sullivan, S. Schumann, R. Da Campo, T. Howells, A. Duraud, M. Shipman, R.A. Hatton, T.S. Jones, T. S. Advanced Energy Materials, 2013, 3, 239-244. Chemo- and enantioselective Rh-catalysed hydrogenation of 3-methylene-1,2-diazetidines: application to vicinal diamine synthesis G.P. Iacobini, D.W. Porter, M. Shipman, Chem. Commun. 2012, 9852-9854. Aziridine Scaffolds for the Detection and Quantification of Hydrogen-Bonding Interactions through Transition-State Stabilization L. Giordano, C.T. Hoang, M. Shipman, J.H.R. Tucker, T.R. Walsh, Angew. Chem. Int. Ed. 2011, 50, 741-744