Our research focuses on the synthesis of macromolecules with highly controlled and pre-determinable structures using modern polymer and organic synthetic methods. We exploit supramolecular interactions to organise these molecules into nanostructured materials, for applications in nanomedicine (e.g. drug delivery, vaccines, antimicrobial materials - our materials are tested in house and in our group at the Monash Institute for Pharmaceutical Sciences (MIPS) in Melbourne, Australia), nanotechnology (e.g. components for optoelectronic applications), materials science (e.g. rheology modifiers) or chemistry (catalysis, processes, etc.).

Research projects in the group cover:

i/ fundamental understanding of polymerization mechanisms,

ii/ development of synthetic strategies to make functional polymeric architectures,

iii/ self-assembly via supramolecular interaction, and

iv/ engineering of nanostructured materials.

Cobo, I.; Li, M.; Sumerlin, B. S.; Perrier, S. Smart hybrid materials by conjugation of responsive polymers to biomacromolecules, Nature Mat. 2015, 14 (2), 143-159 Gody, G.; Danial, M.; Barbey, R.; Perrier, S. Ultrafast RAFT Polymerization: Multiblock Copolymers within Minutes, Polym. Chem., 2015, 6, 1502-1511 Moraes, J.; Ohno, K.; Maschmeyer, T.; Perrier, S., Selective Patterning of Gold Surfaces by Core-Shell, Semi-Soft Hybrid Nanoparticles, Small 2015, 11 (4), 482-488 Danial, M.; My-Nhi Tran, C.; Jolliffe, K.A. Perrier, S. Thermal Gating in Lipid Membranes Using Thermoresponsive Cyclic PeptidePolymer Conjugates, J. Am. Chem. Soc. 2014, 136 (22), 8018-8026 Gody, G.; Maschmeyer, T.; Zetterlund, P.B.; Perrier, S. Pushing the Limit of the RAFT Process: Multiblock Copolymers by One-Pot Rapid Multiple Chain Extensions at Full Monomer Conversion, Macromolecules 2014, 47(10), 3451-3460 Janus cyclic peptide–polymer nanotubes, Danial, M.; My-Nhi Tran, C.; Young, P.G.; Perrier, S.; Jolliffe, K.A., Nat. Commun. 2013, DOI:10.1038/ncomms3780 Rapid and Quantitative One-Pot Synthesis of Sequence-Controlled Polymers by Radical Polymerization, Gody, G.; Maschmeyer, T.; Zetterlund, P.B.; Perrier, S., Nat. Commun., 2013, DOI: 10.1038/ncomms3505 Structure elucidation and control of cyclic peptide-derived nanotube assemblies in solution, Chapman, R.; Koh, M.L.; Warr, G.G; Jolliffe, K.A.; Perrier, S. Chem. Sci., 2013, 4 (6), 2581 - 2589 Synthesis of Silica-Polymer Core-Shell Nanoparticles by Reversible Addition-Fragmentation Chain Transfer Polymerization, Moraes, J.; Ohno, K.; Maschmeyer, T.; Perrier, S. Chem. Commun., 2013, 49 (80), 9077 - 9088 Multi-Shell Soft Nanotubes from Cyclic Peptide Templates, Chapman, R.; Jolliffe, K.A.; Perrier, S. Adv. Mater., 2013, 25, 1170–1172 Monodisperse, Charge-Stabilized, Core–Shell Particles via Silica-Supported Reversible Addition–Fragmentation Chain Transfer Polymerization for Cell Imaging, Moraes, J.; Ohno, K.; Maschmeyer, T.; Perrier, S., Chem. Mater., 2013, 25 (17), 3522–3527