Gunn-Moore, Frank
Prof
所属大学: University of St Andrews
所属学院: School of Biology
个人主页:
http://biology.st-andrews.ac.uk/contact/staffProfile.aspx?sunid=fjg1
个人简介
BSc. Biological Sciences, University of Edinburgh PhD. Department of Biochemistry, University of Cambridge Post-doctoral, Department of Biochemistry, University of Bristol and Department of Pre-clinical Veterinary Sciences, University of Edinburgh Lecturer, Senior Lecturer, Reader, Professor, School of Biology, University of St Andrews Invited and elected Fellow of the Royal Society of Biology
近期论文
Aitken, L, Baillie, G, Pannifer, A, Morrison, A, Jones, PS, Smith, TK, McElroy, SP & Gunn-Moore, FJ 2017, 'In vitro assay development and HTS of small molecule human ABAD/17β-HSD10 inhibitors as therapeutics in Alzheimer’s Disease' SLAS Discovery, vol In press. DOI: 10.1177/247255521769796 Hroch, L, Guest, P, Benek, O, Soukup, O, Janockova, J, Dolezal, R, Kuca, K, Aitken, L, Smith, TK, Gunn-Moore, F, Zala, D, Ramsay, RR & Musilek, K 2017, 'Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer’s disease treatment' Bioorganic & Medicinal Chemistry, vol 25, no. 3, pp. 1143-1152. DOI: 10.1016/j.bmc.2016.12.029 Benek, O, Hroch, L, Aitken, L, Dolezal, R, Guest, P, Benkova, M, Soukup, O, Musil, K, Hughes, R, Kuca, K, Smith, TK, Gunn-Moore, F & Musilek, K 2017, '6-benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17β-HSD10 and potential drugs for Alzheimer's disease treatment: design, synthesis and in vitro evaluation' Medicinal Chemistry, vol 13. DOI: 10.2174/157340641366170109142725 Tilston-Lunel, AM, Haley, K, Schlecht, N, Wang, Y, Chatterton, ALD, Moleirinho, SL, Watson, A, Hundal, H, Prystowsky, M, Gunn-Moore, FJ & Reynolds, PA 2016, 'Crumbs 3b promotes tight junctions in an ezrin-dependent manner in mammalian cells' Journal of Molecular Cell Biology, vol 8, no. 5, pp. 439-455. DOI: 10.1093/jmcb/MJW020 Mielenz, D & Gunn-Moore, FJ 2016, 'Physiological and pathophysiological functions of Swiprosin-1/EFhd2 in the nervous system' Biochemical Journal, vol 473, no. 16, pp. 2429-2437. DOI: 10.1042/BCJ20160168