Career History

2015 - present: Lecturer, Dept. of Molecular Biology and Microbiology, University of Sheffield, UK 2010 - 2015: Postdoctoral Fellow, National Institutes of Health, Bethesda, MD, USA 2006 - 2009: Postdoctoral Researcher, Dept. of Physics, University of Oxford, UK 2002 - 2006: PhD., Chemistry, National University of Singapore 1995 - 2000: BSc. (Honors), Chemistry, National University of Singapore

Multidisciplinary techniques such as single-molecule imaging, synthetic biology, biochemistry and microfluidics to study the molecular mechanisms of spatial organization in bacteria, such as cell division and chromosome segregation.

Vecchiarelli AG, Li M, Mizuuchi M, Hwang LC, Seol Y, Neuman KC & Mizuuchi K (2016) Membrane-bound MinDE complex acts as a toggle switch that drives Min oscillation coupled to cytoplasmic depletion of MinD. Proceedings of the National Academy of Sciences, 113(11), E1479-E1488. Robb NC, Cordes T, Hwang LC, Gryte K, Duchi D, Craggs TD, Santoso Y, Weiss S, Ebright RH & Kapanidis AN (2013) The Transcription Bubble of the RNA Polymerase–Promoter Open Complex Exhibits Conformational Heterogeneity and Millisecond-Scale Dynamics: Implications for Transcription Start-Site Selection. Journal of Molecular Biology, 425(5), 875-885. Vecchiarelli AG, Hwang LC & Mizuuchi K (2013) Cell-free study of F plasmid partition provides evidence for cargo transport by a diffusion-ratchet mechanism. Proceedings of the National Academy of Sciences, 110(15), E1390-E1397. Hwang LC, Vecchiarelli AG, Han Y-W, Mizuuchi M, Harada Y, Funnell BE & Mizuuchi K (2013) ParA-mediated plasmid partition driven by protein pattern self-organization. The EMBO Journal, 32(9), 1238-1249. Cordes T, Santoso Y, Tomescu AI, Gryte K, Hwang LC, Camará B, Wigneshweraraj S & Kapanidis AN (2010) Sensing DNA Opening in Transcription Using Quenchable Förster Resonance Energy Transfer. Biochemistry, 49(43), 9171-9180. Heilemann M, Hwang LC, Lymperopoulos K & Kapanidis AN (2009) Single-molecule FRET analysis of protein-DNA complexes. Methods in Molecular Biology, 543, 503-521. Hwang LC & Wohland T (2007) Recent Advances in Fluorescence Cross-correlation Spectroscopy. Cell Biochemistry and Biophysics, 49(1), 1-13. Liu P, Sudhaharan T, Koh RML, Hwang LC, Ahmed S, Maruyama IN & Wohland T (2007) Investigation of the Dimerization of Proteins from the Epidermal Growth Factor Receptor Family by Single Wavelength Fluorescence Cross-Correlation Spectroscopy. Biophysical Journal, 93(2), 684-698.