We are interested in how cells move and how this movement, or migration, is controlled. Cell migration is an essential part of many normal biological processes and also many diseases. For example, during an infection cells of the immune system move towards the site of infection and during wound healing cells need to move to the site of injury in order to repair the damage. Cell migration is also important in the spread of cancer and a better understanding of this process is essential for improving the treatment of a wide range of diseases.

Dannoura, A., Giraldo, A., Pereira, I., Gibbins, J., Dash, P., Bicknell, K. and Brooks, G. (2014) Ibuprofen inhibits migration and proliferation of human coronary artery smooth muscle cells by inducing a differentiated phenotype: role of peroxisome proliferator-activated receptor y. Journal of Pharmacy and Pharmacology, 66 (6). pp. 779-792. ISSN 0022-3573 doi: 10.1111/jphp.12203 Khanna, S., Dash, P. R. and Darbre, P. D. (2014) Exposure to parabens at the concentration of maximal proliferative response increases migratory and invasive activity of human breast cancer cells in vitro. Journal of Applied Toxicology, 34 (9). pp. 1051-1059. ISSN 0260-437X doi: 10.1002/jat.3003 Collins-Hooper, H., Sartori, R., Macharia, R., Visanuvimol, K., Foster, K., Matsakas, A., Flasskamp, H., Ray, S., Dash, P., Sandri, M. and Patel, K. (2014) Propeptide-mediated inhibition of myostatin increases muscle mass through inhibiting proteolytic pathways in aged mice. Journals of Gerontology Series A: Biological and Medical Sciences, 69 (9). pp. 1049-1059. ISSN 1079-5006 doi: 10.1093/gerona/glt170