Biomolecular Chemistry Infection and Immunity Medicinal Chemistry Molecular Genetics and Genomics

Oyarzun, Patricio, Ellis, Jonathan J., Gonzalez-Galarza, Faviel F., Jones, Andrew R, Middleton, Derek, Boden, Mikael and Kobe, Bostjan (2015) A bioinformatics tool for epitope-based vaccine design that accounts for human ethnic diversity: Application to emerging infectious diseases.. Vaccine, 33 10: 1267-1273. doi:10.1016/j.vaccine.2015.01.040 Ve, Thomas, Williams, Simon J. and Kobe, Bostjan (2014) Structure and function of Toll/interleukin-1 receptor/resistance protein (TIR) domains.. Apoptosis, 20 2: 250-261. doi:10.1007/s10495-014-1064-2 Williams, Simon J., Sohn, Kee Hoon, Wan, Li, Bernoux, Maud, Sarris, Panagiotis, Segonzac, Cecile, Ve, Thomas, Ma, Yan, Saucet, Simon B., Ericsson, Daniel J., Casey, Lachlan W., Lonhienne, Thierry, Winzor, Donald J., Zhang, Xiaoxiao, Coerdt, Anne, Parker, Jane E., Dodds, Peter N., Kobe, Bostjan and Jones, Jonathan D. G. (2014) Structural basis for assembly and function of a heterodimeric plant immune receptor. Science, 344 6181: 299-303. doi:10.1126/science.1247357 Cou?ago, Rafael M., Ween, Miranda P., Begg, Stephanie L., Bajaj, Megha, Zuegg, Johannes, O'Mara, Megan L., Cooper, Matthew A., McEwan, Alastair G., Paton, James C., Kobe, Bostjan and McDevitt, Christopher A. (2014) Imperfect coordination chemistry facilitates metal ion release in the Psa permease. Nature Chemical Biology, 10 1: 35-41. doi:10.1038/nCHeMBIO.1382 Ullah, M. Obayed, Ve, Thomas, Mangan, Matthew, Alaidarous, Mohammed, Sweet, Matthew J., Mansell, Ashley and Kobe, Bostjan (2013) The TLR signalling adaptor TRIF/TICAM-1 has an N-terminal helical domain with structural similarity to IFIT proteins. Acta Crystallographica Section D: Biological Crystallography, 69 12: 2420-2430. doi:10.1107/S0907444913022385 Alaidarous, Mohammed Abdullah, Ve, Thomas, Casey, Lachlan, Valkov, Eugene, Ericsson, Daniel, Obayed, Ullah, M., Schembri, Mark A., Mansell, Ashley, Sweet, Matthew J. and Kobe, Bostjan (2013) Mechanism of bacterial interference with TLR4 signaling by Brucella TIR-domain-containing protein TcpB. Journal of Biological Chemistry, 289 2: 654-668. doi:10.1074/jbc.M113.523274 Ve, Thomas, Williams, Simon J., Catanzariti, Ann-Maree, Rafiqi, Maryam, Rahman, Motiur, Ellis, Jeffrey G., Hardham, Adrienne R., Jones, David A., Anderson, Peter A., Dodds, Peter N. and Kobe, Bostjan (2013) Structures of the flax-rust effector AvrM reveal insights into the molecular basis of plant-cell entry and effector-triggered immunity. Proceedings of the National Academy of Sciences of the United States of America, 110 43: 17594-17599. doi:10.1073/pnas.1307614110