Inorganic Chemistry

Our research interests centre on the genetic modification of haem iron enzymes. Iron is the most widely used metal catalyst in biological systems, and haem enzymes, such as peroxidases, catalyses and monooxygenases, catalyse a number of key chemical reactions. We aim to study the role of individual amino acids in enzyme activity, and to use genetically engineered enzymes to carry out chemical transformations, e.g. C-H bond activation, which are difficult to achieve using conventional methods.