My research interests lie in the use of mathematical models to aid our understanding of the evolution and spread of infectious agents. This encompasses modelling of the dynamics of infections and immune responses within individual hosts as well as models of the spread of infections from one host to another. My group's current research interests focus on:

HIV HCV Influena Scrapie

Arinaminpathy N., McLean A.R. (2008) Antiviral treatment for the control of pandemic influenza: some logistical constraints. J. R. Soc Interface 5: 545-553 Fryer, H.R., Baylis, M., Sivam, K., McLean, A.R. (2007) Quantifying the risk from ovine BSE and the impact of control strategies Proc Biol Sci. 274: 1497-503 R. Asquith A.R. McLean. (2007) In vivo CD8+ T Cell Killing of Immunodeficiency Virus-Infected Cells in Humans and Macaques PNAS 104: 6365-70 R. Asquith, C.T.T. Edwards, M. Lipsitch, A. R. McLean (2006) Inefficient Cytotoxic T Lymphocyte-Mediated Killing of HIV-1-Infected Cells In Vivo (2007) PLOS Biology 4: e90 A. Scherer J. Frater A. Oxenius J. Agudelo, D. A. Price, H. F. Günthard, M. Barnardo, L. Perrin, B. Hirschel, R. E. Phillips, A. R. McLean (2004) Quantifiable CTL responses and HLA-related risk of progression to AIDS PNAS 10112266-12270