Dr. Fogg's research in organometallic chemistry and catalysis focuses on design and discovery of highly active, robust, and selective catalysts, for applications ranging from pharmaceutical synthesis to tissue engineering. A particular focus is on important problems in the rapidly evolving area of olefin metathesis, and highly efficient "tandem" catalysis, in which a single catalyst precursor affects multiple reaction types. A recent area of investigation, which has triggered much industrial and academic interest, centers on development of MALDI mass spectrometry as a tool for structural and mechanistic insight in organometallic chemistry and catalysis.

Dr. Fogg's research in organometallic chemistry and catalysis focuses on design and discovery of highly active, robust, and selective catalysts, for applications ranging from pharmaceutical synthesis to tissue engineering. A particular focus is on important problems in the rapidly evolving area of olefin metathesis, and highly efficient "tandem" catalysis, in which a single catalyst precursor affects multiple reaction types. A recent area of investigation, which has triggered much industrial and academic interest, centers on development of MALDI mass spectrometry as a tool for structural and mechanistic insight in organometallic chemistry and catalysis.

Our research program focuses on the design, understanding, and implementation of transition-metal catalysis for important organic reactions. In particular, we seek to articulate and address important problems of productivity and selectivity in olefin (alkene) metathesis and related methodologies, and tandem catalysis. Applications range from pharmaceutical and fine-chemicals synthesis to materials science and tissue engineering.

Drouin, S.D., G.P.A. Yap, and D. E. Fogg. Hydrogenolysis of A Ruthenium Carbene: Mechanistic Implications for Tandem ROMP-Hydrogenation. Inorg. Chem., 39, 5412-5414., 2000 Drouin, S.D., F. Zamanian, and D.E. Fogg. Multiple Tandem Catalysis: Facile Cycling between Hydrogenation and Metathesis Chemistry. Organometallics, 20, 5495-5497., 2001 Conrad, J.C., H.H. Parnas, and D.E. Fogg. Ruthenium-Pseudohalide Complexes: Efficient Catalysts for Olefin Metathesis. J. Am. Chem. Soc., 11882-11883., 2005 Conrad, J.C., M.D. Eelman, J. Silva, S. Monfette, H. Parnas, J.L. Snelgrove, and D.E. Fogg. Oligomers as Intermediates in Ring-Closing Metathesis. J. Am. Chem. Soc., 129, 1024-1025., 2007 Camm, K.D., N. Martinez Castro, Y. Liu, P. Czechura, J.L. Snelgrove, and D.E. Fogg. Tandem ROMP-Hydrogenation with Third-Generation Grubbs Catalysts. J. Am. Chem. Soc., 129, 4168-4169., 2007