Melancon, Charles E. (Chad) III
Assistant Professor
所属大学: University of New Mexico
所属学院: Department of Chemistry and Chemical Biology
邮箱:
cemelanc@unm.edu
个人主页:
http://chemistry.unm.edu/people/faculty/members/chad-melancon.html
个人简介
Education BS Biology, BA Chemistry, 2001, The University of New Orleans PhD Biochemistry, 2006, The University of Texas at Austin NIH Kirschstein Postdoctoral Fellow, 2007-2010, The Scripps Research Institute
研究领域
Chemical Biology and Biochemistry Pharmaceutical Chemistry
Natural product genome mining and comparative genomics Natural product drug discovery and chemical ecology Natural product biosynthesis Development of natural product detection systems Development of novel strategies for manipulation of natural product biosynthetic pathways
近期论文
Guo, J.†;Melançon, C. E., III†; Lee, H. S.; Groff, D.; Schultz, P. G. Evolution of Amber Suppressor tRNAs for Efficient Bacterial Production of Proteins Containing Nonnatural Amino Acids. Ang. Chem. Int. Ed. 2009, 48, 9148-9151.
Thibodeaux, C. J.; Melançon, C. E., III; Liu, H.-w. Natural Product Sugar Biosynthesis and Enzymatic Glycodiversification. Ang. Chem. Int. Ed. 2008, 51, 9814-9859.
Zhang, H.; White, J. A.; Melançon, C. E., III; Kwon, H.-j.; Yu, W.-l.; Liu, H.-w. Elucidation of the Kijanimicin Gene Cluster: Insights into the Biosynthesis of Spirotetronate Antibiotics and Nitrosugars. J. Am. Chem. Soc. 2007, 129, 14670-14683.
Thibodeaux, C. J.; Melançon, C. E., III; Liu, H.-w. Unusual Sugar Biosynthesis and Natural Product Glycodiversification. Nature 2007, 446, 1008-1016.
Melançon, C. E., III; Liu, H.-w. Engineered Biosynthesis of Macrolide Derivatives Bearing the Non- Natural Deoxysugars 4-epi-D-Mycaminose and 3-N-Monomethylamino-3-Deoxy-D-Fucose. J. Am. Chem. Soc. 2007, 129, 4896-4897.