Melancon, Charles E. (Chad) III 照片

Melancon, Charles E. (Chad) III

Assistant Professor

所属大学: University of New Mexico

所属学院: Department of Chemistry and Chemical Biology

邮箱:
cemelanc@unm.edu

个人主页:
http://chemistry.unm.edu/people/faculty/members/chad-melancon.html

个人简介

Education BS Biology, BA Chemistry, 2001, The University of New Orleans PhD Biochemistry, 2006, The University of Texas at Austin NIH Kirschstein Postdoctoral Fellow, 2007-2010, The Scripps Research Institute

研究领域

Chemical Biology and Biochemistry Pharmaceutical Chemistry

Natural product genome mining and comparative genomics Natural product drug discovery and chemical ecology Natural product biosynthesis Development of natural product detection systems Development of novel strategies for manipulation of natural product biosynthetic pathways

近期论文

Guo, J.†;Melançon, C. E., III†; Lee, H. S.; Groff, D.; Schultz, P. G. Evolution of Amber Suppressor tRNAs for Efficient Bacterial Production of Proteins Containing Nonnatural Amino Acids. Ang. Chem. Int. Ed. 2009, 48, 9148-9151.

Thibodeaux, C. J.; Melançon, C. E., III; Liu, H.-w. Natural Product Sugar Biosynthesis and Enzymatic Glycodiversification. Ang. Chem. Int. Ed. 2008, 51, 9814-9859.

Zhang, H.; White, J. A.; Melançon, C. E., III; Kwon, H.-j.; Yu, W.-l.; Liu, H.-w. Elucidation of the Kijanimicin Gene Cluster: Insights into the Biosynthesis of Spirotetronate Antibiotics and Nitrosugars. J. Am. Chem. Soc. 2007, 129, 14670-14683.

Thibodeaux, C. J.; Melançon, C. E., III; Liu, H.-w. Unusual Sugar Biosynthesis and Natural Product Glycodiversification. Nature 2007, 446, 1008-1016.

Melançon, C. E., III; Liu, H.-w. Engineered Biosynthesis of Macrolide Derivatives Bearing the Non- Natural Deoxysugars 4-epi-D-Mycaminose and 3-N-Monomethylamino-3-Deoxy-D-Fucose. J. Am. Chem. Soc. 2007, 129, 4896-4897.