Cardiovascular Physiology (Vascular physiology, endothelium, arterial remodelling, extracellular matrix, relaxin, acute heart failure) Maternal Physiology in Pregnancy (Vascular physiology, blood pressure, placenta, relaxin, preeclampsia)

Adverse vascular remodelling is more sensitive than endothelial dysfunction to hyperglycaemia in diabetic rat mesenteric arteries. Pharmacological Research. 111. 2016 Relaxin deficiency results in increased expression of angiogenesis- and remodelling-related genes in the uterus of early pregnant mice but does not affect endometrial angiogenesis prior to implantation. Reproductive Biology and Endocrinology. 14. 2016 Serelaxin (recombinant human relaxin-2) prevents high glucose-induced endothelial dysfunction by ameliorating prostacyclin production in the mouse aorta. Pharmacological Research. 107. 2016 Serelaxin: A Novel Therapaeutic for Vascular Diseases. Trends in Pharmacological Sciences. 37. 2016 Time-dependent activation of prostacyclin and nitric oxide pathways during continuous i.v. infusion of serelaxin (recombinant human H2 relaxin). British Journal of Pharmacology. 173. 2016