How Ebola and Marburg viruses interact with the cell’s signal transduction pathways for their own purpose of evading the host’s antiviral systems. Specifically, I have shown that an activated Ras signalling pathway is required for robust Ebola virus protein synthesis and that the activated Ras pathway may be enhancing the viral protein translation through the suppression of the host cells interferon system. I am currently looking into which elements downstream of the Ras-signalling pathway are required for this enhancement of viral infection in hope to suppress these pathways and thereby suppress viral infection.