multidrug resistance in Gram-negative bacteria, Resistance-Nodulation-Division efflux pumps, Acinetobacter, Pseudomonas, pathogenicity and virulence, bacterial stress response, genomics and transcriptomics

Fernando, D., Xu, W., Loewen, P. C., Zhanel, G. G., and Kumar, A. (2014) Triclosan can select for AdeIJK overexpressing mutant of Acinetobacter baumannii ATCC17978 that displays reduced susceptibility to multiple antibiotics. Antimicrobial Agents and Chemotherapy, 58:6424-6431. Loewen, P. C., Alsaadi, Y., Fernando, D., Kumar, A. (2014) Genome sequence of a tigecycline-resistant clinical isolate of Acinetobacter baumannii strain AB031 obtained from a bloodstream infection. Genome Announcements, 2:pii: e01036-14. Loewen, P. C., Alsaadi, Y., Fernando, D., Kumar, A. (2014) Genome sequence of an extremely drug-resistant clinical isolate of Acinetobacter baumannii strain AB030. Genome Announcements, 2:pii: e01035-14. Moya-Torres, A., Mulvey, M. R., Kumar, A., Oresnik, I. J., and Brassinga, A. K. C. (2014) The lack of OmpF, but not OmpC, contributes to increased antibiotic resistance in Serratia marcescens. Microbiology, 160:1882-1892. Bazyleu, A and Kumar, A. (2014) Incubation temperature, osmolarity, and salicylate affect the expression of Resistance-Nodulation-Division efflux pumps and outer membrane porins in Acinetobacter baumannii ATCC19606T. FEMS Microbiology Letters, 357(2):136-143. Tilley, D., Law, R., Warren, S., Samis, J., and Kumar, A. (2014) CpaA a novel protease from Acinetobacter baumannii clinical isolates deregulates blood coagulation. FEMS Microbiology Letters, 356: 53-61. (Editor's choice for the issue) Fernando, D. and Kumar, A. (2013) Resistance-nodulation-division multidrug efflux pumps in Gram-negative bacteria: role in virulence. Antibiotics, 2: 163-181. Fernando, D., Zhanel, G. G., and Kumar, A. (2013) Antibiotic resistance and expression of resistance-nodulation-division pumps and outer membrane porins in Acinetobacter spp isolated from Canadian hospitals. Canadian Journal of Infectious Diseases and Medical Microbiology, 24: 17-21. Fernando, D. and Kumar, A. (2012) Growth phase-dependent expression of RND efflux pump- and outermembrane porin-encoding genes in Acinetobacter baumannii ATCC19606. Journal of Antimicrobial Chemotherapy, 67:569-572.