1987 B.S. University of Illinois–Urbana 1992 Ph.D. Harvard University

Biochemistry: Mechanistic Enzymology

Enzymology tRNA Modification Sulfur Transfer Bioorganic Mechanism

Crystal Structure of Pseudouridine Synthase RluA: Indirect Sequence Readout through Protein-Induced RNA Structure C. Hoang, J. Chen, C. A. Vizthum, J. M. Kandel, C. S. Hamilton, E. G. Mueller, and A. R. Ferré-d'Amaré Mol. Cell 2006, 24, 535-545

Mechanistic Investigations of the Pseudouridine Synthase RluA Using RNA Containing 5-Fluorouridine C. S. Hamilton, T. M. Greco, C. A. Vizthum, J. M. Ginter, M. V. Johnston, and E. G. Mueller Biochemistry 2006, 39, 12019-12038

Direct evidence for enzyme persulfide and disulfide intermediates during 4-thiouridine biosynthesis C. M. Wright, G. D. Christman, A. M. Snellinger, M. V. Johnston, and E. G. Mueller Chem. Comm. 2006, 3104-3106

Trafficking in persulfides: delivering sulfur in biosynthetic pathways E. G. Mueller Nature Chem. Biol.2006, 4, 185-194