Optimisation of the synthesis of second generation 1,2,4,5 tetraoxane antimalarials Selective inhibitors of Cyclophilin D to treat Pancreatitis Small Molecule Inhibitors of Cyclophilin D To Protect Mitochondrial Function as a Potential Treatment for Acute Pancreatitis Artemisinin-Polypyrrole Conjugates: Synthesis, DNA Binding Studies and Preliminary Antiproliferative Evaluation