Structure function analysis of the small airways in diseases such as asthma and COPD to enable early detection: this includes imaging (both CT and MRI systems), computational modelling and small airway physiology. Evaluation of airway remodelling in asthma and its association with disease persistence and progression. Phenotyping and biomarkers of airways disease with a focus on both volatile detection (translational lead for the MRC-EMBER molecular pathology node program) and non-volatile liquid particles in air. In collaboration with the Department of Mathematics at Leicester, Salman chairs the Data Analysis and Modelling in Medicine (DAMM) group(http://dammgroup.webs.com/) and is interested in the development of statistical approaches applied to complex data to understand disease phenotypes.