May, Celia A. 照片

May, Celia A.

Dr

所属大学: University of Leicester

所属学院: School of Biological Sciences

邮箱:
cam5@le.ac.uk

个人主页:
http://www2.le.ac.uk/departments/genetics/people/may

研究领域

I am interested in understanding fundamental processes like mutation and recombination which generate DNA diversity and thus contribute to disease and drive evolution

近期论文

Berg IL, Neumann R, Lam KWG, Sarbajna S, Odenthal-Hesse L, May CA & Jeffreys AJ. PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans Nature Genet. 42, 859-863 (2010) Kauppi L, May CA & Jeffreys AJ (2009) Analysis of meiotic recombination products from human sperm. Methods Mol Biol 557:323-355. Shanks ME, May CA, Dubrova YE, Balaresque P, Rosser ZH, Adams SM & Jobling MA (2008) Complex germline and somatic mutation processes at a haploid human minisatellite shown by single-molecule analysis Mutation Research 648:46-53. May CA, Slingsby MT & Jeffreys AJ (2007) Human recombination hotspots: before and after the HapMap project. Pages 195-244 in “Recombination and meiosis; crossing over and disjunction” volume of the “Genome Dynamics and Stability” series, eds. R. Egel & D. Lankenau, Springer Berlin/Heidelberg. Jeffreys AJ & May CA (2004) Intense and highly localised gene conversion activity in human meiotic crossover hot spots. Nature Genetics 36(2):151-156. Jeffreys AJ, Holloway JK, Kauppi L, May CA, Neumann R, Slingsby MT & Webb AJ (2004) Meiotic recombination hotspots and human DNA diversity. Philosophical Transactions of the Royal Society, London series B 359(1441):141-152. Jeffreys AJ & May CA (2003) DNA enrichment by allele-specific hybridization (DEASH): a novel method for haplotyping and for detecting low frequency base-substitutional variants and recombinant DNA molecules. Genome Research 13:2316-2324. May CA, Shone AC, Kalaydjieva L, Sajantila A & Jeffreys AJ (2002) Crossover clustering and rapid decay of linkage disequilibrium in the Xp/Yp pseudoautosomal gene SHOX. Nature Genetics 31:272-275. May CA, Tamaki K, Neumann R, Wilson G, Zagars G, Pollack A, Dubrova YE, Jeffreys AJ & Meistrich ML (2000) Human minisatellite sperm mutation frequency following radiotherapy. Mutation Research 453: 67-75. Rogers EJ, Shone AC, Alonso S, May CA & Armour JAL (2000) Integrated analysis of sequence evolution and population history using hypervariable compound haplotypes. Human Molecular Genetics 9: 2675-2681. Monteiro C, Marcelino LA, Conde AR, Saraiva C, Giphart-Gassler M, De Nooij-van Dalen AG, Van Buuren-van Seggelen V, Van der Keur M, May CA, Armour JAL, Lehmann AR, Steingrimsdottir H, Beare D, Capulas E & Cole J (2000) Molecular methods for the detection of mutations. Teratogenesis, Carcinogenesis and Mutagenesis 20: 357-386. Korpim?ki E, May CA, Parkin DT, Wetton JH & Wiehn J (2000) Environmental and parental condition related variation in sex ratio of kestrel broods. Journal of Avian Biology 31: 128-134. doi:10.1034/j.1600-048X.2000.310204.x Jeffreys AJ, Barber R, Bois P, Buard J, Dubrova YE, Hollies CRH, May CA, Neumann R, Panayi M, Ritchie AE, Shone AC, Signer E, Stead JDH and Tamaki K (1999) Human minisatellites, repeat DNA instability and meiotic recombination. Electrophoresis 20: 1665-1675. He Q, Cederberg H, Armour JAL, May CA & Rannug U (1999) Polarity and orientation-dependence of inter-allelic exchanges at human minisatellite MS205 in yeast. Gene 232: 143-153. Tamaki K, May CA, Dubrova YE & Jeffreys AJ (1999) Extremely complex repeat shuffling during germline mutation at human minisatellite B6.7. Human Molecular Genetics 8: 879-888. Jeffreys AJ, Bois P, Buard J, Collick A, Dubrova Y, Hollies CR, May CA, Murray J, Neil DL, Neumann R, Stead JDH, Tamaki K, Yardley J (1997) Spontaneous and induced minisatellite instability. Electrophoresis 18: 1501-1511. May CA, Jeffreys AJ & Armour JAL (1996) Mutation rate heterogeneity and the generation of allele diversity at the human minisatellite locus MS205 (D16S309). Human Molecular Genetics 5: 1823-1833. Armour JAL, Anttinen T, May CA, Vega EE, Sajantila A, Kidd JR, Kidd KK, Bertranpetit J, P??bo S & Jeffreys AJ (1996) Minisatellite diversity supports a recent African origin for modern humans. Nature Genetics 13:154-160. Korpim?ki E, Lahti K, May CA, Parkin DT, Powell GB, Tolonen P & Wetton JH (1996) Copulatory behaviour & paternity determined by single-locus profiling in kestrels: effects of cyclic food abundance. Animal Behaviour.51:945-955. doi:10.1006/anbe.1996.0098 Jeffreys AJ, Allen MJ, Armour JAL, Collick A, Dubrova Y, Fretwell N, Guram T, Jobling M, May CA, Neil DL & Neumann R (1995) Mutation processes at human minisatellites. Electrophoresis 16: 1577-1585. Zeh DW, Zeh JA & May CA (1994) Charomid cloning vectors meet the pedipalpal chelae: single-locus minisatellite probes for paternity assignment in the harlequin beetle-riding pseudoscorpion. Molecular Ecology 3: 517-522. May CA, Wetton JH & Parkin DT (1993) Polymorphic sex-specific sequences in birds of prey. Proceedings of the Royal Society of London, series B 253: 271-276. doi:10.1098/rspb.1993.0113 Zeh DW, May CA, Coffroth MA & Bermingham E (1993) Mbo I and Macrohaltica - quality of DNA fingerprints is strongly enzyme-dependent in an insect (Coleoptera). Molecular Ecology 2: 61-63. doi:10.1111/j.1365-294X.1993.tb00100.x5 May CA, Wetton JH, Davis PE, Brookfield JFY & Parkin DT (1993) Single-locus profiling reveals loss of variation in inbred populations of the Red Kite (Milvus milvus). Proceedings of the Royal Society of London, series B 251: 165 – 170. doi:10.1098/rspb.1993.0024 May CA & Wetton JH (1991) DNA fingerprinting by specific priming of concatenated oligonucleotides. Nucleic Acids Research 19: 4557.