Professor Pogorelov received a Diploma in Biomedical Engineering from Bauman Moscow State Technical University in 1995, an M.S. in Mathematics in 1996, and a Ph.D. in Chemical Physics in 2006, both from the University of Illinois at Urbana-Champaign. From 2006 to 2009 he was a postdoctoral research associate in Chemistry Department and from 2009 to 2012 he was a postdoctoral research associate at the Beckman Institute and a Research Scientist at the School of Chemical Sciences. In 2012 he was appointed a Senior Research Scientist in charge of scientific computing, where he advises and collaborates with the School’s researchers in the areas of advanced computational chemistry.

My research interests are in application and development of computational methods for modeling of biological macromolecules using the frameworks of molecular dynamics, quantum chemistry, and molecular evolution. Current emphasis is on the membrane associated phenomena, membrane structure and membrane-protein interactions.

Prigozhin, M.B., Chao, S.-H., Pogorelov*, T.V., and Gruebele*, M. “Mapping fast protein folding with multiple-site fluorescent probes,” Under revision.

Vermaas, J.V., Baylon, J.L., Arcario, M.J., Muller, M., Wu, Z., Pogorelov, T.V., and Tajkhorshid., E. “Efficient Exploration of Membrane-Associated Phenomena at Atomic Resolution,” Submitted.

Skeby, K.K., Pogorelov, T.V., Tajkhorshid, E., and Schi?tt,B., “Determining the aggregation prone structure of hIAPP using a highly mobile membrane model,” To be submitted.

Pogorelov, T.V., Vermaas, J. V., Arcario, M.J., and Tajkhorshid, E., “Partitioning of amino acids into a model membrane: capturing the interface,” J. Phys. Chem. B., 118, 1481–1492, 2014.

Goodman, J.S., Chao, S.-H., Pogorelov*, T.V., and Gruebele*, M., “Filling up the heme pocket stabilizes apomyoglobin and speeds up its folding,” J. Phys. Chem. B., 118, 6511?6518, 2014.

Ohkubo Y.Z., Pogorelov T.V., Arcario M.J., Christensen G., and Tajkhorshid E., “The Membrane Mimetic Model for Rapid and Spontaneous Membrane Binding of Membrane-Anchoring Proteins,” 102, 2130-2139, 2012. Free Access, Cover Art, Blog Entry, DOI:10.1016/j.bpj.2012.03.015, PMCID: PMC3341550

Tavoosi, N., Davis-Harrison, R.L., Pogorelov, T.V., Ohkubo, Y.Z., Arcario, M.J., Clay, M.C., Rienstra, C.M., Tajkhorshid, E., and Morrissey, J.H., “Molecular determinants of phospholipid synergy in blood clotting,” J. Biol. Chem., 286, 23247-23253, 2011. Free Access, Cover Art, Press Release, DOI: 10.1074/jbc.M111.25176, PMCID: PMC3123091

Morrissey, J.H, Davis-Harrison, R.L., Tavoosi, N., Ke, K., Pureza, V., Boettcher, J.M., Clay, M.C., Rienstra, C.M., Ohkubo, Y.Z., Pogorelov, T.V., Tajkhorshid, E. “Protein-phospholipid interactions in blood clotting.” Thromb. Res., 125, S23-S25, 2010. Free Access. DOI:10.1016/j.thromres.2010.01.027, PMCID: PMC2838931

Virshup, A.M., Punwong, C., Pogorelov, T.V., Lindquist, B.A., Ko, C., and Marti?nez, T.J., “Photodynamics in complex environments: ab initio multiple spawning quantum mechanical/molecular mechanical dynamics,” J. Phys. Chem. B., 113, 3280-3291, 2009. Feature article. DOI: 10.1021/jp8073464, PMID: 19090684

Pogorelov, T.V., Autenrieth F., Roberts, E. and Luthey-Schulten, Z., " Cytochrome c2 exit strategy: dissociation studies and evolutionary implications,” J. Phys. Chem. B., 111, 618-634, 2007. Cover Article. DOI: 10.1021/jp064973i, PMID: 17228920

Pogorelov, T. V. and Luthey-Schulten, Z., "Variations of the fast folding rates of λ-repressor: a hybrid molecular dynamics study," Biophysical J., 87, 207-214, 2004. DOI: 10.1529/biophysj.104.042861, PMCID: PMC1304343

Hardin C., Pogorelov T.V., and Luthey-Schulten Z., “Ab initio protein structure prediction,” Curr. Op. Struc. Bio., 12, 176-181, 2002. DOI:10.1016/S0959-440X(02)00306-8, PMID: 11959494