2004 PhD Insect Molecular Biology (University of Nottingham/Rothamsted Research) 2000 Biology (University of Nottingham) Career

2016 – present Chair in Applied Entomology – University of Exeter

2015 – present ERC Consolidator Fellow

2014 – 2015 Principal Research Scientist– Rothamsted Research

2009 – 2014 BBSRC Institute Career Path Fellow

2004 – 2009 Postdoctoral Research Fellow – Rothamsted Research

Our group’s research exploits recent advances in transcriptomics, genomics and post-genomic functional approaches to understand adaptive evolution in insects. A significant focus of our work is understanding how insects detoxify the natural and synthetic xenobiotics they encounter in the environment. This includes both plant secondary metabolites and man-made insecticides.

Zimmer CT, Garrood WT, Puinean AM, Eckel-Zimmer M, Williamson MS, Davies TG, Bass C (2016). A CRISPR/Cas9 mediated point mutation in the alpha 6 subunit of the nicotinic acetylcholine receptor confers resistance to spinosad in Drosophila melanogaster. Insect Biochem Mol Biol, 73, 62-69. Abstract. Author URL. Full text. Article has an altmetric score of 1 Garrood WT, Zimmer CT, Gorman KJ, Nauen R, Bass C, Davies TGE (2016). Field-evolved resistance to imidacloprid and ethiprole in populations of brown planthopper Nilaparvata lugens collected from across South and East Asia. Pest Management Science, 72(1), 140-149. Abstract. Alptekin S, Bass C, Nicholls C, Paine MJ, Clark SJ, Field L, Moores GD (2016). Induced thiacloprid insensitivity in honeybees (Apis mellifera L.) is associated with up-regulation of detoxification genes. Insect Mol Biol, 25(2), 171-180. Abstract. Author URL. Full text. Article has an altmetric score of 3 Bass C, Jones CM (2016). Mosquitoes boost body armor to resist insecticide attack. Proc Natl Acad Sci U S A, 113(33), 9145-9147. Author URL. Full text. Article has an altmetric score of 14 Silva WM, Berger M, Bass C, Williamson M, Moura DMN, Ribeiro LMS, Siqueira HAA (2016). Mutation (G275E) of the nicotinic acetylcholine receptor α6 subunit is associated with high levels of resistance to spinosyns in Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae). Pesticide Biochemistry and Physiology, 131, 1-8. Abstract. Full text. Panini M, Tozzi F, Bass C, Zimmer CT, Field L, Borzatta V, Mazzoni E, Moores G (2016). The interactions between piperonyl butoxide and analogues with the metabolic enzymes FE4 and CYP6CY3 of the green peach aphid Myzus persicae (Hemiptera: Aphididae). Pest Manag Sci Abstract. Author URL. Jones CM, Papanicolaou A, Mironidis GK, Vontas J, Yang Y, Lim KS, Oakeshott JG, Bass C, Chapman JW (2015). Genomewide transcriptional signatures of migratory flight activity in a globally invasive insect pest. MOLECULAR ECOLOGY, 24(19), 4901-4911. Author URL. Full text. Article has an altmetric score of 4 Troczka BJ, Williams AJ, Bass C, Williamson MS, Field LM, Davies TG (2015). Molecular cloning, characterisation and mRNA expression of the ryanodine receptor from the peach-potato aphid, Myzus persicae. Gene, 556(2), 106-112. Abstract. Author URL. Article has an altmetric score of 1 Abeku TA, Helinski ME, Kirby MJ, Kefyalew T, Awano T, Batisso E, Tesfaye G, Ssekitooleko J, Nicholas S, Erdmanis L, et al (2015). Monitoring changes in malaria epidemiology and effectiveness of interventions in Ethiopia and Uganda: Beyond Garki Project baseline survey. Malar J, 14 Abstract. Author URL. Full text. Article has an altmetric score of 5 Zhang Y, Wang X, Yang B, Hu Y, Huang L, Bass C, Liu Z (2015). Reduction in mRNA and protein expression of a nicotinic acetylcholine receptor α8 subunit is associated with resistance to imidacloprid in the brown planthopper, Nilaparvata lugens. J Neurochem, 135(4), 686-694. Abstract. Author URL. Silva WM, Berger M, Bass C, Balbino VQ, Amaral MH, Campos MR, Siqueira HA (2015). Status of pyrethroid resistance and mechanisms in Brazilian populations of Tuta absoluta. Pestic Biochem Physiol, 122, 8-14. Abstract. Author URL. Article has an altmetric score of 1 Bass C, Denholm I, Williamson MS, Nauen R (2015). The global status of insect resistance to neonicotinoid insecticides. Pestic Biochem Physiol, 121, 78-87. Abstract. Author URL. Article has an altmetric score of 8 Zimmer CT, Maiwald F, Schorn C, Bass C, Ott MC, Nauen R (2014). A de novo transcriptome of European pollen beetle populations and its analysis, with special reference to insecticide action and resistance. Insect Mol Biol, 23(4), 511-526. Abstract. Author URL. Dabiré RK, Namountougou M, Diabaté A, Soma DD, Bado J, Toé HK, Bass C, Combary P (2014). Distribution and frequency of kdr mutations within Anopheles gambiae s.l. populations and first report of the ace.1 G119S mutation in Anopheles arabiensis from Burkina Faso (West Africa). PLoS One, 9(7). Abstract. Author URL. Full text. Zimmer CT, Bass C, Williamson MS, Kaussmann M, Wölfel K, Gutbrod O, Nauen R (2014). Molecular and functional characterization of CYP6BQ23, a cytochrome P450 conferring resistance to pyrethroids in European populations of pollen beetle, Meligethes aeneus. Insect Biochem Mol Biol, 45, 18-29. Abstract. Author URL. Article has an altmetric score of 1 Bass C, Puinean AM, Zimmer CT, Denholm I, Field LM, Foster SP, Gutbrod O, Nauen R, Slater R, Williamson MS, et al (2014). The evolution of insecticide resistance in the peach potato aphid, Myzus persicae. Insect Biochemistry and Molecular Biology, 51(1), 41-51. Abstract. Full text. Vezenegho SB, Chiphwanya J, Hunt RH, Coetzee M, Bass C, Koekemoer LL (2013). Characterization of the Anopheles funestus group, including Anopheles funestus-like, from Northern Malawi. Transactions of the Royal Society of Tropical Medicine and Hygiene, 107(12), 753-762. Abstract. Puinean AM, Elias J, Slater R, Warren A, Field LM, Williamson MS, Bass C (2013). Development of a high-throughput real-time PCR assay for the detection of the R81T mutation in the nicotinic acetylcholine receptor of neonicotinoid-resistant Myzus persicae. Pest Manag Sci, 69(2), 195-199. Abstract. Author URL. Namountougou M, Diabaté A, Etang J, Bass C, Sawadogo SP, Gnankinié O, Baldet T, Martin T, Chandre F, Simard F, et al (2013). First report of the L1014S kdr mutation in wild populations of Anopheles gambiae M and S molecular forms in Burkina Faso (West Africa). Acta Tropica, 125(2), 123-127. Abstract. Bass C, Zimmer CT, Riveron JM, Wilding CS, Wondji CS, Kaussmann M, Field LM, Williamson MS, Nauen R (2013). Gene amplification and microsatellite polymorphism underlie a recent insect host shift. Proceedings of the National Academy of Sciences of the United States of America, 110(48), 19460-19465. Abstract.