NMR spectroscopy, mass spectrometry, analysis of complex mixtures, molecular structure and dynamics, carbohydrate structure, protein-carbohydrate complexes, NMR pulse sequence development

Bell, N.G.A., Michalchuk, A. A.L., Blackburn, J. W. T., Graham, M.C., Uhrín, D., Isotope-Filtered 4D NMR Spectroscopy for Structure Determination of Humic Substances. Angew. Chem. Int. Ed. 54, 8382 –8385 (2015). Blaum, B.S., Hannan, J.P., Herbert, A.P., Kavanagh, D., Uhrín, D, Stehle, T. Structural basis for sialic acid-mediated self-recognition by complement factor H, Nature Chem. Biol. 11, 77–82 (2015). Bell, N.G.A., Murray, L., Graham, M., Uhrín, D., NMR methodology for complex mixture ‘separation’. Chem. Commun. 50, 1694-1697 (2014). Panagos, C.G., Thomson, D.S., Moss, C., Hughes, A.D., Kelly, M.S., Liu, Y., Chai, W., Venkatasamy, R., Spina, D., Page, C.P., Hogwood, J., Woods, R.J., Mulloy, B., Bavington, C.D., Uhrín, D. Fucosylated chondroitin sulfates from the body wall of the sea cucumber Holothuria forskali. Conformation, selectin binding and biological activity. J. Biol. Chem. 289, 28284–28298 (2014). Bell, N.G.A, Rigg, G., Masters, S., Bella, J., Uhrín, D. Detecting low-level flexibility using residual dipolar couplings: a study of the conformation of cellobiose, Phys. Chem. Chem. Phys.15, 18223-18234 (2013).