Photophysics and photochemistry, time-resolved fluorescence spectroscopy, fluorescence lifetime imaging microscopy, DNA conformation and interactions, microfluidics

2-Aminopurine flipped into the active site of the adenine-specific DNA methyltransferase M.TaqI:crystal structures and time-resolved fluorescence, T. Lenz, E.Y.M. Bonnist, G.Pljevaljcic, R.K. Neely, D.T.F. Dryden, A.J. Scheidig, A.C. Jones, E. Weinhold, J. Am. Chem. Soc 2007, 129, 6240-6248. Photophysics and X-ray structure of crystalline 2-aminopurine, R.K. Neely, S.W. Magennis, S.Parsons, A.C. Jones, ChemPhysChem 2007, 8, 1095-1102. High-precision FLIM-FRET in fixed and living cells reveals heterogeneity in a simple CFP-YFP fusion protein, M. Millington, J.G. Grindlay, K. Altenbach, R.K. Neely,W. Kolch, M. Bencina, N.D. Read, A.C. Jones, D.T.F Dryden, S.W. Magennis, Biophysical Chemistry 2007, 127, 155-164. Structural characterisation of the photoisomers of reactive sulfonated azo dyes by NMR spectroscopy and DFT calculations, K.M. Tait, J.A. Parkinson, D.I. Gibson, P.R. Richardson, W.J. Ebenezer, M.G. Hutchings and A.C. Jones, Photochem. Photobiol. Sci (in press, published on web 20 April 2007) Influence of Base Dynamics on the Conformational Properties of DNA: Observation of Static Conformational States in Rigid Duplexes at 77 K, R.K. Neely and A.C. Jones, J. Am. Chem. Soc. 2006, 128, 15952-15923 Time-resolved fluorescence of 2-aminopurine as a probe of base flipping in M.HhaI-DNA complexes. R.K. Neely, D. Daujotyte, S. Grazulis, S.W. Magennis, D.T.F. Dryden, S. Klimasauskas, A.C. Jones, Nucleic Acids Research, 2005, 33, 6953-6960. Quantitative spatial mapping of mixing in microfluidic systems. S.W. Magennis, E.M. Graham, A.C. Jones, Angew. Chem. Int. Ed. 2005, 44, 6512-6516