Campopiano, Dominic
Professor
所属大学: University of Edinburgh
所属学院: School of Chemistry
邮箱:
dominic.campopiano@ed.ac.uk
个人主页:
http://www.chem.ed.ac.uk/staff/academic-staff/professor-dominic-campopiano
研究领域
Natural product biosynthesis, enzymology, protein structure, antibiotics, innate immunity enzyme inhibitors
近期论文
Raman, M. C., Johnson, K. A., Yard, B. A., Lowther, J., Carter, L. G., Naismith, J. H. & Campopiano, D. J. The external-aldimine form of serine palmitoyltranserase; structural, kinetic and spectroscopic analysis of the wild-type enzyme and HSAN1 mutant mimics. J. Biol. Chem., 2009, 284, 17328-17339 Lowther, J., McMahon, S., Johnson, K. A., Yard, B. A., Carter, L. G Raman, M. C., Naismith, J. H. & Campopiano, D. J. Serine palmitoyltranserase displays a novel mechanism of cycloserine inhibition. Molecular Biosystems, 2010, 6, 1682-1693 Bhat, V. T., Caniard, A. M., Luksch, T., Brenk, R., Campopiano, D. J.,* & Greaney, M. F.* Nucleophilic catalysis of acylhydrazone equilibration for protein-directed dynamic covalent chemistry. Nature Chemistry, 2010, 2, 490-497 Campopiano, D. J., Clarke, D. J., Polfer, N. C., Barran, P. E., Langley, R. J., Govan, J. R. W., Maxwell, A., & Dorin, J. R. Structure-activity relationships in defensin dimers. J. Biol. Chem., 2004, 279 (47), 48671-48679 Ortega, X. P., Cardona, S. T., Brown, A. R., Loutet, S. A., Flannagan, R. S., Campopiano, D. J., Govan, J. R. W., & Valvano, M. A. A putative gene cluster for aminoarabinose biosynthesis is essential for Burkholderia cenocepacia viability. J. Bacteriol., 2007, 189, 3639-3644