Anja obtained a degree in Biology at the University of the Saar in Saarbruecken, Germany in 1995. She then went on to undertake a PhD at the Institute of Virology at the University Hospital in Homburg/Saar, Germany. After finishing her PhD she carried out postdoctoral research with Philip Strange at the University of Reading (1999-2002) and then joined the group of James Pease at Imperial College London (2003-2004). She joined UEA in August 2004 as a Lecturer in Molecular Pharmacology and was promoted to Senior Lecturer in 2009.

Anja's primary research interest is the investigation of cell signalling mechanisms of chemokine receptors which are a subgroup of G-protein-coupled receptors. She is interested in how the expression of these receptors is regulated on the cell surface and how they activate heterotrimeric G-proteins and other intracellular signalling pathways to induce cell migration.

Mills, S. C., Goh, P. H., Kudatsih, J., Ncube, S., Gurung, R., Maxwell, W., Mueller, A.(2016)Cell migration towards CXCL12 in leukemic cells compared to breast cancer cellsin Cellular Signalling28.pp. 316-324 Full Text UEA Repository(Article) Jacques, R. O., Mills, S. C., Cazzonatto Zerwes, P., Fagade, F. O., Green, J. E., Downham, S., Sexton, D. W., Mueller, A.(2015)Dynamin function is important for CC-chemokine receptor induced cell migrationin Cell Biochemistry and Function33.pp. 407-414 Full Text UEA Repository(Article) Kerr, J., Jacques, R., Moyano Cardaba, C., Tse, T., Sexton, D., Mueller, A.(2013)Differential regulation of chemotaxis: Role of Gβγ in chemokine receptor-induced cell migrationin Cellular Signalling25.pp. 729-735 Full Text UEA Repository(Article) Khabbazi, S., Jacques, R., Moyano Cardaba, C., Mueller, A.(2013)Janus kinase 2 and signal transducer and activator of transcription 3 activation is not essential for CCL3-, CCL5- or CCL8-induced chemotaxisin Cell Biochemistry and Function31.pp. 312-318 Full Text UEA Repository(Article) Ahire, J. H., Chambrier, I., Mueller, A., Bao, Y., Chao, Y.(2013)Synthesis of D-Mannose Capped Silicon Nanoparticles and Their Interactions with MCF-7 Human Breast Cancerous Cellsin ACS Applied Materials & Interfaces5.pp. 7384-7391 Full Text UEA Repository(Article) Redshaw, C., Watkins, S., Humphrey, S. M., Bulman Page, P. C., Ashby, S., Chao, Y., Herbert, C. J., Mueller, A.(2013)Rhenium(i) phenanthrolines bearing electron withdrawing CF3 substituents: synthesis, characterization and biological evaluationin RSC Advances3.pp. 23963-23966 Full Text UEA Repository(Article) Redshaw, C., Elsegood, M., Frese, J., Ashby, S., Chao, Y., Mueller, A.(2012)Cellular uptake studies of two hexanuclear, carboxylate bridged, zinc ring structures using fluorescence microscopyin Chemical Communications48.pp. 6627-6629 Full Text UEA Repository(Article) Redshaw, C., Elsegood, M., Wright, J., Baillie-Johnson, H., Yamato, T., Giovanni, S., Mueller, A.(2012)Cellular uptake of a fluorescent vanadyl sulfonylcalix[4]arenein Chemical Communications48.pp. 1129-1131 Full Text UEA Repository(Article) Moyano, C., Jacques, R., Barrett, J., Hassell, K., Kavanagh, A., Remington, F., Tse, T., Mueller, A.(2012)CCL3 induced migration occurs independently of intracellular calcium releasein Biochemical and Biophysical Research Communications418.pp. 17-21 Full Text UEA Repository(Article) Mueller, A., Lalor, R., Moyano Cardaba, C., Matthews, S.(2011)Stable and sensitive probes for lysosomes: Cell-penetrating fluorescent calix[4]arenes accumulate in acidic vesiclesin Cytometry Part A79A.pp. 126-136 Full Text UEA Repository(Article) Howell, L., Gulam, R., Mueller, A., O'Connell, M., Searcey, M.(2010)Design and synthesis of threading intercalators to target DNAin Bioorganic & Medicinal Chemistry Letters1.pp. 6956-6959 Full Text UEA Repository(Article) Howell, L., Howman, A., O'Connell, M., Mueller, A., Searcey, M.(2009)Synthesis and evaluation of 9-aminoacridines derived from benzyne click chemistryin Bioorganic & Medicinal Chemistry Letters19.pp. 5880-5883 Full Text UEA Repository(Article) Cardaba, C. M., Mueller, A.(2009)Distinct modes of molecular regulation of CCL3 induced calcium flux in monocytic cellsin Biochemical Pharmacology78.pp. 974-982 Full Text UEA Repository(Article) Kerr, J., Mueller, A.(2009)Functional selectivity of CCR5 interaction with heterotrimeric G-proteinsin FEBS Journal276.pp. 237-237 UEA Repository(Article) Cardaba, C. M., Kerr, J. S., Mueller, A.(2008)CCR5 internalisation and signalling have different dependence on membrane lipid raft integrityin Cellular Signalling20.pp. 1687-1694 Full Text UEA Repository(Article) Meiser, A., Mueller, A., Wise, E. L., McDonagh, E. M., Petit, S. J., Saran, N., Clark, P. C., Williams, T. J., Pease, J. E.(2008)The chemokine receptor CXCR3 is degraded following internalization and is replenished at the cell surface by de novo synthesis of receptorin Journal of Immunology180.pp. 6713-6724 UEA Repository(Article) Lalor, R., Baillie-Johnson, H., Redshaw, C., Matthews, S., Mueller, A.(2008)Cellular Uptake of a Fluorescent Calix[4]arene Derivativein Journal of the American Chemical Society130.pp. 2892-2893 Full Text UEA Repository(Article) Mueller, A., Meiser, A., McDonagh, E. M., Fox, J. M., Petit, S. J., Xanthou, G., Williams, T. J., Pease, J. E.(2008)CXCL4-induced migration of activated T lymphocytes is mediated by the chemokine receptor CXCR3in Journal of Leukocyte Biology83.pp. 875-882 Full Text UEA Repository(Article) Egesten, A., Eliasson, M., Johansson, H. M., Olin, A. I., Morgelin, M., Mueller, A., Pease, J. E., Frick, I. M., Bjorck, L.(2007)The CXC chemokine MIG/CXCL9 is important in innate immunity against Streptococcus pyogenesin Journal of Infectious Diseases195.pp. 684-693 Full Text UEA Repository(Article) Lalor, R., DiGesso, J. L., Mueller, A., Matthews, S. E.(2007)Efficient gene transfection with functionalised multicalixarenesin Chemical Communicationspp. 4907-4909 Full Text UEA Repository(Article)