Muqit, Miratul 照片

Muqit, Miratul

Dr

所属大学: University of Dundee

所属学院: School of Life Sciences

邮箱:
m.muqit@dundee.ac.uk

个人主页:
http://www.lifesci.dundee.ac.uk/people/miratul-muqit

近期论文

Iovino M, Pfisterer U, Holton JL, Lashley T, Swingler RJ, Calo L, Treacy R, Revesz T, Parmar M, Goedert M, Muqit MMK*, Spillantini MG* (2013)The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons.Acta Neuropath in press DOI: 10.1007/s00401-013-1219-1 (*Joint Senior Authors) Kondapalli C, Kazlauskaite A, Zhang N, Woodroof HI, Campbell DG, Gourlay R, Burchell L, Walden H, Macartney TJ, Deak M, Knebel A, Alessi DR, & Muqit MMK (2012)PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65.Open Biol 2, 120080 (30 citations) Woodroof HI, Pogson JH, Begley M, Cantley LC, Deak M, Campbell DG, van Aalten DM, Whitworth AJ, Alessi DR, & Muqit MMK. (2011)Discovery of catalytically active orthologues of the Parkinson’s disease kinase PINK1: analysis of substrate specificity and impact of mutations.Open Biol 1, 11001. (9 citations) Sleiman, PM*, Healy DG*, Muqit MMK*, Yang YX, Van Der Brug M, Holton JL, et al. (2009)Characterisation of a novel NR4A2 mutation in Parkinson’s disease brain.Neurosci Lett 457: 75-79. (*Joint 1st Author) (13 citations) Moran NF, Banin MD, Muqit MMK, Bax BE. (2008)Carrier erythrocyte entrapped thymidine phosphorylase therapie for mngie.Neurology 71: 686-688 (30 citations) Abou-Sleiman PM, Muqit MMK, McDonald NQ et al. (2006)A heterozygous effect for PINK1 mutations in Parkinson’s disease; low frequency low penetrance?Ann Neurol 60, 414-419 (93 citations) Muqit MMK, Abou-Sleiman PM, Saurin A, et al. (2006)Altered cleavage and localisation of PINK1 in the presence of proteasomal stress.J Neurochem 98, 156-169 (83 citations) Gandhi S, Muqit MMK, Healy DG et al. (2006)PINK1 protein in normal human brain and Parkinson’s disease.Brain 129, 1720-1731 (172 citations) Valente EM, Abou-Sleiman PM, Caputo V*, Muqit MMK*, Harvey K, Gispert S, Ali Z et al. (2004)Hereditary early onset Parkinson’s disease is caused by mutations in PINK1.Science 304, 1158-1160. (*Joint 2nd author) (1193 citations) Muqit MMK, Davidson SM, Payne-Smith MD, MacCormac LP, Wood NW, Latchman DS. (2004)Parkin is recruited into aggresomes in a stress specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival. Hum Mol Genet 13, 117-135 (58 citations)