Land, Stephen
Dr
所属大学: University of Dundee
所属学院: School of Life Sciences
近期论文
Tosoni K, Cassidy D, Kerr B, Land SC, Mehta A. Using Drugs to Probe the Variability of Trans-Epithelial Airway Resistance. PLoS One. 11(2):e0149550, 2016. Land, S.C. D. Walker and C. L Scott. mTOR signalling, embryogenesis and the control of lung development. Semin Cell Dev Biol. 36:68-78, 2014 Luijten NH, SG Basten, T Claessens, M Vernooij, CL Scott, R Janssen, JA. Easton, M A. F. Kamps, M Vreeburg, JLV Broers, M van Geel, FH. Menko, RP. Harbottle, RK. Nookala, AR Tee, SC. Land, R Giles, BJ. Coull, and MAM. van Steensel. Birt-Hogg-Dubé syndrome is a novel ciliopathy Hum. Mol. Genet, 22(21):4383-97, 2013. Watt GB, Ismail NA, Garcia Caballero A, Land SC, Wilson SM. Epithelial Na+ channel activity in human airway epithelial cells: the role of Serum and glucocorticoid-inducible kinase 1. Br J Pharmacol. 166(4):1272-89.2012. Dunlop, EA, KM. Dodd, SC Land, PA. Davies, N Martins, H Stuart, S McKee, C Kingswood, A Saggar, Isabel Corderio, AM Duarte Medeira, H Kingston, JR. Sampson, DM Davies and AR. Tee. Determining the Pathogenicity of Patient-Derived TSC2 Mutations by Functional Characterisation and Clinical Evidence. Eur J. Hum Genetics. 19(7):789-95, 2011. Preston, RS, A. Philp, T. Claesens, EA Dunlop, L. Gijezen, KT Harper, T. Brinkhuizen, M. Davies, SC Land, K. Baar, A. Pause, M van Steensel, and AR. Tee. Absence of the Birt Hogg Dubé gene product is associated with increased Hypoxia Inducible Factor transcriptional activity and a Warburg effect. Oncogene 30(10):1159-73, 2010. Scott CL, Walker DJ, Cwiklinski EL, Tait C, Tee AR, Land SC. Control of HIF-1? and vascular signalling in fetal lung involves cross-talk between mTORC1 and the FGF-10/FGFR2b/Spry2 airway branching periodicity clock. Am J Physiol Lung Cell Mol Physiol. 299(4):L455-71, 2010.(Editorial highlight). Hunter MJ, Treharne KJ, Winter AK, Cassidy DM, Land SC, Mehta A. Expression of wild-type CFTR suppresses NF-?B-driven inflammatory signalling. PLoS One. 5(7):p1-9, 2010. Land SC, Tee AR. Hypoxia-Inducible Factor 1? is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif. J Biol Chem. 282(28):20534-43, 2007. Land, S.C. and C. Rae. iNOS initiates and sustains metabolic arrest in hypoxic lung adenocarcinoma cells: a mechanism of cell survival in the solid tumor core. Am. J. Physiol. Cell Physiol. 289:C918-C933, 2005. (Impact factor: 3.71) Land, S.C. and S.M. Wilson. Redox regulation of lung development and perinatal lung epithelial function. Invited review: Antioxidants and Redox Signaling, 7(1&2):92-107, 2005. Land, S.C. Hochachka’s “Hypoxia Defense Strategies” and the development of the pathway for oxygen. Invited Review: Comp. Biochem. Physiol. A (Molec. Integ. Physiol).139(3): 415-433, 2004 Land, S.C. and A. Collett. Detection of Cl- flux in the apical microenvironment of cultured foetal distal lung epithelial cells. J. Exp. Biol. 204: 785-795, 2001. V.M.F. Almeida-Val, A.L. Val, W.P. Duncan, F.C.A. Souza, M.N. Paula-Silva and S.C. Land. Scaling effects on hypoxia tolerance in the Amazon fish Astronotus ocellatus (Perciformes: Cichlidae): contribution of tissue enzyme levels, Comp. Biochem. Physiol. (Biochem. Mol. Biol) 125 (2): 219-226, 2000. Land, S.C., D.M. Porterfield, R.H. Sanger and P.J.S. Smith. The self-referencing oxygen-selective microelectrode: detection of transmembrane O2 flux from single cells. J. Exp. Biol. 202: 211-218, 1999. Hochachka, P.W., L.T. Buck, C.J. Doll and S.C. Land. Unifying theory of hypoxia tolerance: Molecular/metabolic defense and rescue mechanisms for surviving oxygen lack. Proc. Natl. Acad. Sci. U.S.A. 93:9493-9498, 1996. Land, S.C. and P.W. Hochachka. A heme-protein based oxygen-sensing mechanism controls the expression and suppression of multiple proteins in anoxia-tolerant turtle hepatocytes. Proc. Natl. Acad. Sci. USA, 92: 7505-7509, 1995.