Jeremy Lambert obtained his PhD from Strathclyde University, followed by postdoctoral training at the Department of Pharmacology (University of Connecticut, USA) and the Department of Zoology, University of Nottingham. In 1981, he was appointed to a lectureship in Pharmacology at Dundee University, being made Professor of Neuropharmacology in 1991. Together with Professor David G Nicholls, in 1995 he established the Neuroscience Institute at Dundee University to facilitate the interaction of clinical and scientific neuroscience researchers. With Professor Tim Hales funding was raised to create the Institute of Academic Anaesthesia in 2009. From 1999 - 2011, he was the Head of the Neuroscience Institute (now the Division of Neuroscience). In 1999, he was presented with the Gaddum Memorial Award by the British Pharmacological Society, in 2000 the Gold Medal for “Distinguished Services to Anaesthesia” and in 2002 was the British Pharmacological Society visitor to Australia. He was made a Fellow of the Royal Society of Edinburgh (2004); Fellow of the British Pharmacological Society (2004) and a Fellow of the Royal College of Anaesthetists (2010). He is currently a co-director of the Wellcome Trust clinical PhD programme at Dundee University.

His main research interests concern synaptic transmission in the central nervous system.

Stephens, D.N., King, S.L., Lambert, J.J., Belelli, D., Duka, T. (2017). GABAA receptor subtype involvement in addictive behaviour. Genes Brain Behav., 16(1): 149 – 184. Kumar, N., Fagarrt, J., Liere, P., Mitchell, S.J., Knibb, A.R., Petit-Topin, I., Rame, M., El-Etr, M., Schumacher, M., Lambert, J.J., Rafestin-Oblin, M.E., Sitruk-Ware, R. (2016) Nesterone (NES) a novel progestin for non-oral contraception: Structure activity relationships & brain metabolism studies. Endocrinology (Nov 8th Epub ahead of print) Brown, A.R., Mitchell, S.J., Peden, D.R., Herd, M.B., Seifi, M., Swinny, J.D., Belelli, D., Lambert, J.J. (2016). During postnatal development endogenous neurosteroids influence GABA-ergic neurotransmission of mouse cortical neurons. Neuropharmacology 103: 163-173. Brown, A.R., Herd, M.B. Belelli, D. and Lambert, J.J. (2015) Developmentally regulated neurosteroid synthesis enhances GABAergic neurotransmission in mouse thalamocortical neurones." J. Physiol. 593(1): 267-284. Corteen, N.L., Carter, J.A., Rudolph, U., Belelli, D., Lambert, J.J., Swinny, J.D. (2015). Localisation and stress-induced plasticity of GABAA receptor subunits within the cellular networks of the mouse dorsal raphe nucleus. Brain Structure & Function 220(5): 2739-63. Gunn, B.G., Cunningham, L., Mitchell S., Swinny, J.D., Lambert, J.J., Belelli, D. (2015) GABAA receptor-acting neurosteroids: a role in the development and regulation of the stress response. Front. in Neuroendocrinology 36: 28-48. Golovko, T., Min, R., Lozovaya, N., Falconer, C., Yatsenko, N., Tsintsadze, T., Tsintsadze, V., Ledent, C., Harvey, R.J., Belelli, D., Lambert, J.J., Rozov, A., Burnashev, N. (2015). Control of Inhibition by the Direct Action of Cannabinoids on GABAA Receptors. Cerebral Cortex. 25(9): 2440-2455. Ling, I.,Mihalek, B., Etherington, L.A., Kapus, G., Palvolgi, A., Gigler, G., Kertesz, S., Gaal, A., Pallagi, K., Kiricsi, P., Szabo, E., Szenasi, G., Papp, L., Harsing, L.G., Levay, G., Spedding, M., Lambert, J.J., Belelli, D., Barkoczy, J., Volk, B., Simig, G., Gacsalyi, I., Anthoni, F.A. (2015). A novel GABAA α5 receptor inhibitor with therapeutic potential. Eur. J. Pharmacol., 764: 497-507. Herd, M.B., Lambert, J.J., Belelli, D. (2014). The general anaesthetic etomidate inhibits the excitability of mouse thalamocortical relay neurones by modulating multiple modes of GABAA receptor-mediated inhibition. Eur J. Neurosci. 40(3): 2487-501 Maguire, E.P., Mitchell, E.A., Greig, S.J. Corteen, N., Balfour, D.J.K, Swinny, J.D., Lambert, J.J., Belelli, D. (2014) Extrasynaptic glycine receptors of rodent dorsal raphe serotonergic neurons: a sensitive target for ethanol. Neuropsychopharmacology 39(5): 1232-1244 Seifi, M., Brown, J., Mills, J., Bhandari, P., Belelli, D., Lambert, J.J., Rudolph, U., Swinny, J. (2014). Molecular and functional diversity of GABAa receptors in the enteric nervous system of the mouse colon. J. Neurosci. 34(31): 10361-78 Anstee, Q.A., Knapp, S., Maguire, E.P., Hosie, A.M., Thomas, P., Mortensen, M., Bhome, R., Martinez, A., Walker, S.E., Dixon, C.I., Ruparelia, K., Montagnese, S., Kuo, Y-T., Herlihy, A., Bell, J.D., Robinson, I., Guerrini, I., McQuillin, A., Fisher, E.M.C., Ungless, M.A., Gurling, H.M.D., Morgan, M.Y., Brown, S.D.M., Stephens, D.N., Belelli, D., Lambert, J.J., Smart, T.G., Thomas, H.C. (2013). Mutations on the Gabrb1 gene promote alcohol consumption through increased tonic inhibition. Nat. Commun. 4: 2816 doi: 10.1038/ncomms3816. Maguire, E.P., Macpherson, T., Swinny, J., Dixon, C.I., Herd, M.B., Belelli, D., Stephens, D.N., King, S.L., Lambert, J.J. (2014). Tonic inhibition of accumbal spiny neurons by extrasynaptic α4bδ GABAA receptors modulates the actions of psychostimulants. J. Neurosci., 34(3): 823-838. Gunn, B.G., Cunningham, L., Cooper, M.A., Corteen, N.L., Seifi, M., Swinny, J.D., Lambert, J.J., Belelli, D. (2013). Dysfunctional astrocytic and synaptic regulation of hypothalamic glutamatergic transmission in a mouse model of early-life adversity: relevance to neurosteroids and programming of the stress response. J. Neurosci. 33 (50): 19534 - 54. Herd, M.B., Brown, A.R., Lambert, J.J., Belelli, D. (2013). Extrasynaptic GABAA receptors couple presynaptic activity to postsynaptic inhibition in the somatosensory thalamus. J. Neurosci., 33(37): 14850 – 68. Wlodarczyk A., Sylantyev S., Herd, M.B., Kersant F., Lambert J.J., Rusakov D, Linthorst, A., Semyanov A., Belelli D, Pavlov I, and Walker M. (2013). GABA-independent GABAA receptor openings maintain tonic currents. J Neurosci. 33(9): 3905-3914. Zhang H, Etherington L.A., Hafner A.S., Belelli D., Coussen F., Delagrange P., Chaouloff F., Spedding M., Lambert J.J. , Choquet D., Groc L. (2013). Regulation of AMPA receptor surface trafficking and synaptic plasticity by a cognitive enhancer and antidepressant molecule. Mol. Psychiatry 18(4): 471-484. Carland, J.E., Cooper, M.A., Livesey, M.R., Hales, T.G., Peters, J.A., Lambert, J.J. (2013). Mutagenic analysis of the intracellular portals of the human 5HT3A receptor. J. Biol. Chem., 288(44): 31592 - 601. Jensen M.L., Wafford K.A., Brown A.R., Belelli D., Lambert J.J., Mirza N.R (2013). A study of subunit selectivity, mechanism and site of action of the delta-selective compound 2 (DS2) at human recombinant and rodent native GABAA receptors. Br. J. Pharmacol. 168(5): 1118-1132. Baptista-Hon, D.T., Deeb, T.Z., Lambert, J.J., Peters, J.A., Hales, T.G. (2013). The minimum M3-M4 loop length of neurotransmitter-activated pentameric receptors is critical for the structural integrity of cytoplasmic portals. J. Biol. Chem. 288(30): 21558-21568. Newman, A.S., Batis, N., Grafton, G., Caputo, F., Brady, C.A., Lambert, J.J., Peters, J.A., Gordon, J., Brain, K.L., Powell, A.D., Barnes, N.M. (2013). 5-Chloroindole: a potent allosteric modulator of the 5-HT3 receptor. Br. J. Pharmacol., 169 (6): 1228-1238. Panzanelli P, Gunn BG, Schlatter MC, Benke D, Tyagarajan SK, Scheiffele P, Belelli D, Lambert J.J., Rudolph U, Fritschy, J-M. (2011). Distinct mechanisms regulate GABAA receptor and gephyrin clustering at perisomatic and axo-axonic synapses on CA1 pyramidal cells. J. Physiol. 589: 4959-80. B.G. Gunn, A.R. Brown, J.J. Lambert, D. Belelli (2011). Neurosteroids and GABAA receptor interactions: A focus on stress. Front. Neurosci. 5: 1-20. M.R. Livesey, M.A. Cooper, Lambert J.J., J.A. Peters (2011). Rings of charge within the extracellular vestibule influence ion permeation of the 5HT3 receptor. J. Biol. Chem. 286: 16008-16017. Dixon, C.L., Morris, H.V., Breen, G., Desrivieres, S., Jugurnauth, S., Steiner, R.C., Vallada, R., Guindalini, C., Lavanjeira, R., Messas, G., Rosahl, T.W., Atack, J.R., Peden, D.R., Belelli, D., Lambert, J.J. , King, S.L., Schumann, G., Stephens, D.N. (2010). Cocaine effects on mouse incentive-learning and human addiction are linked to α2 subunit–containing GABAA receptors. Proc. Natl. Acad. Sci. USA, 107: 2289-2294.