Hormuzdi, Sheriar
Dr
所属大学: University of Dundee
所属学院: School of Life Sciences
个人主页:
http://www.lifesci.dundee.ac.uk/people/sheriar-hormuzdi
个人简介
Sheriar Hormuzdi obtained a PhD from the Ohio State University, USA, and undertook postdoctoral research positions with Paul Bornstein (University of Washington, Seatle) and Hannah Monyer (Heidelberg University, Germany) before being awarded a Research Councils UK academic fellowship to continue research on electrical synapses in 2005.
近期论文
Bargiotas P, Krenz A, Hormuzdi SG, Ridder DA, Herb A, Barakat W, Penuela S, von Engelhardt J, Monyer H, Schwaninger M. 2011. Pannexins in ischemia-induced neurodegeneration. Proc Natl Acad Sci U S A. 108(51):20772-7. Helbig I, Sammler E, Eliava M, Bolshakov AP, Rozov A, Bruzzone R, Monyer H, Hormuzdi SG. 2010. In vivo evidence for the involvement of the carboxy terminal domain in assembling connexin 36 at the electrical synapse. Mol Cell Neurosci. 45(1):47-58. Hines RM, Wu L, Hines DJ, Steenland H, Mansour S, Dahlhaus R, Singaraja RR, Cao X, Sammler E, Hormuzdi SG, Zhuo M, El-Husseini A. 2008. Synaptic imbalance, stereotypies, and impaired social interactions in mice with altered neuroligin 2 expression. J Neurosci. 28(24):6055-67 Youssef FF, Hormuzdi SG, Irving AJ, Frenguelli BG. 2007. Cannabinoid modulation of neuronal function after oxygen/glucose deprivation in area CA1 of the rat hippocampus. Neuropharm. 52(6):1327-35 Butovas S, Hormuzdi SG, Monyer H, Schwarz C. 2006. Effects of electrically coupled inhibitory networks on local neuronal responses to intracortical microstimulation. J Neurophysiol. 96(3):1227-36 Titz, S., Hormuzdi, SG., Lewen, A., Monyer, H., and Misgeld. U. 2006. Functional changes upon overexpression of KCC2 require maturation of cultured neurons. Eur J Neurosci. 23(2):454-64 Vogt, A., Hormuzdi, S.G., Monyer, H. 2005. Pannexin1 and Pannexin2 expression in the developing and mature rat brain. Brain Res Mol Brain Res 141(1):113-20 Christie, J.M., Bark, C., Hormuzdi, S.G., Helbig, I. Monyer, H., and Westbrook, G.L. 2005. Connexin 36-mediated spike synchrony in olfactory bulb glomeruli. Neuron 46:1-12 *Hankenson, K.D., *Hormuzdi, S.G., Meganck, J.A., Bornstein, P. 2005. Mice with a Disruption of the Thrombospondin 3 Gene Differ in Geometric and Biomechanical Properties of Bone and Have Accelerated Development of the Femoral Head. Mol. Cell. Biol. 25(13):5599-606 *Equal contributions Schubert, T., Degen, J., Willecke, K., Hormuzdi, S.G., Monyer, H., Weiler, R. 2005. Connexin36 mediates gap junctional coupling of alpha-ganglion cells in mouse retina. J. Comp. Neurol. 485(3):191-201 Feigenspan, A., Bienhold-Janssen, U., Hormuzdi, S.G., Monyer, H., Degen, J., Sohl, G., Willecke, K., Weiler, R. 2004. Cellular expression of neural connexin 36 in the outer retina of the mouse. J. Neurosci. 24(13):3325-34 Hormuzdi, S.G., Filippov, M.A., Mitropoulou, G., Monyer, H., Bruzzone, R. 2004. Electrical synapses: a dynamic signaling system that shapes the activity of neuronal networks. Biochimica et Biophysica Acta 1662(1-2):113-37 Rahkonnen, O., Su, M., Hakovirta, H., Koskivirta, I., Hormuzdi, S.G., Vuorio, E., Bornstein, P., Penttinen, R. 2004. Mice with a large deletion in the first intron of the Col1a1 gene develop aortic aneurysims. Circ. Res. 94(1):83-90 *Bruzzone, R., *Hormuzdi, S.G., Barbe, M., Herb, A., Monyer, H. 2003. Pannexins, a novel family of gap junction proteins expressed in brain. PNAS 100(23):13644-9. *Equal contributions Filippov, M.A., Hormuzdi, S.G., Fuchs, E.C., Monyer, H. 2003. A reporter allele for investigating connexin 26 gene expression in the mouse brain. Eur. J. of Neurosci. 18(12):3183-92 Blatow, M., Rozov, A., Katona, I., Hormuzdi, S.G., Meyer, A.H., Whittington, M.A., Caputi, A., and Monyer, H. 2003. A novel network of multipolar bursting interneurons generates theta frequency oscillations in neocortex. Neuron 38(5):805-17 Traub, R.D., Pais, I., Bibbig, A., LeBeau, F.E., Buhl, E.H., Hormuzdi, S.G.,Monyer, H., and Whittington, M.A. 2003. Contrasting roles of axonal (pyramidal cell) and dendritic (interneuron) electrical coupling in the generation of neuronal network oscillations. PNAS 100(3):1370-4 Pais, I., Hormuzdi, S.G.,Monyer, H., Traub, R.D., Wood, I.C.,Buhl, E.H., Whittington, M.A., and LeBeau, F.E. 2003. Sharp wave-like activity in the hippocampus in vitro in mice lacking the gap junction protein connexin 36. J. Neurophysiol. 89(4):2046-54 Buhl, D.L., Harris, K.D., Hormuzdi, S.G., Monyer, H., and Buzsáki, G. 2003. Selective impairment of hippocampal gamma oscillations in connexin-36 knockout mouse in vivo. J. Neurosci. 23(3):1013-8 Bornstein, P., Walsh, V., Tullis, J., Stainbrook, E., Bateman, J.F., Hormuzdi, S.G. 2002. The globular domain of the pro alpha1(I) N-propeptide is not required for secretion, processing by procollagen N-proteinase, or fibrillogenesis of type I collagen in mice. J. Biol. Chem. 277(4):2605-13 Kelsch, W., Hormuzdi, S.G., Straube, E., Lewen, A., Monyer, H., Misgeld, U. 2001. Insulin-like growth factor 1 and a cytosolic tyrosine kinase activate chloride outward transport during maturation of hippocampal neurons. J. Neurosci. 21(21): 8339-47 Hormuzdi, S.G., Pais, I., LeBeau, F.E., Towers, S.K., Rozov, A., Buhl, E.H., Whittington, M.A., Monyer, H. 2001. Impaired electrical signaling disrupts gamma frequency oscillations in connexin 36-deficient mice. Neuron 31(3):487-95 Hormuzdi, S.G., Strandjord, T.P., Madtes, D.K., and Bornstein, P. 1999 Mice with a targeted deletion in the Col1a1 gene respond to bleomycin-induced pulmonary fibrosis with increased expression of the mutant allele. Matrix Biol. 18(3):287-294. Hormuzdi, S.G., Penttinen, R., Jaenisch, R., and Bornstein, P. 1998 A gene targeting approach identifies a function for the first intron in expression of the a1(I) collagen gene. Mol. Cell. Biol. 18(6): 3368-3375. Liu, X., Wu, H., Loring, J., Hormuzdi, S.G., Disteche, C.M., Bornstein, P., and Jaenisch, R. 1997. Trisomy eight in ES cells is a common potential problem in gene targeting and interferes with germ line transmission. Dev.Dyn. 209(1):85-91.