Hopkins, Andrew
Professor
所属大学: University of Dundee
所属学院: School of Life Sciences
近期论文
The role of ligand efficiency measures in drug discovery. Hopkins, A.L., Kereru, G.M., Leeson, P.D., Rees, D.C. and Reynolds, C.H. Nature Reviews Drug Discovery, 2013 (accepted). Discovery of b-adrenergic receptor ligands using biosensor fragment screening of tagged wild-type receptor. Aristotelous, T., Ahn, S., Shukla, A.K., Gawaron, S., Sassano, M.F., Kahsai, A.W., Wingler, L.M., Zhu, X., Tripathi-Shukla, P., Huang, X.-P., Riley, J., Besnard, J., Read, K.D., Roth, B.L., Gilbert, I.H., Hopkins, A.L., Lefkowitz, R.J. and Navratilova, I. ACS Med.Chem.Letts 2013, (4 (10), 1005-1010). De novo design of ligands against multi-target profiles. Besnard, J. and Hopkins, A.L. In De Novo Molecular Design, Ed: Gisbert Schneider, Wiley, 2013. Automated design of ligands to polypharmacological profiles. Jérémy Besnard, Gian Filippo Ruda, Vincent Setola, Keren Abecassis, Ramona M. Rodriguiz, Xi-Ping Huang, Suzanne Norval, Maria F. Sassano, Antony I. Shin, Lauren A. Webster, Frederick R.C. Simeons, Laste Stojanovski, Annik Prat, Nabil G. Seidah, Daniel B. Constam, G. Richard Bickerton, Kevin D. Read, William C. Wetsel, Ian H. Gilbert, Bryan L. Roth and Andrew L. Hopkins, Nature, (2012)492, 215–220 doi:10.1038/nature11691