Dr Fuller gained his BA in Pharmacology from University of Cambridge (Emmanuel College) and remained in the Department of Pharmacology in Cambridge to study for a PhD investigating the misfolding of the F508 mutant of CFTR under the supervision of the then head of department Professor AW Cuthbert. He then moved on to King's College London (St Thomas Hospital campus) where he worked on regulation of the cardiac sodium pump in the laboratory of Professor Michael Shattock. During 8 years in this lab Dr Fuller developed interests in the hormonal regulation of cardiac ion transport - working first on the sodium pump, and later on its cardiac accessory protein phospholemman. He moved to Dundee in 2006 to establish an independent research lab with a specific interest in protein-protein interactions and post-translational modifications in cardiac muscle.

Pavlovic, D., Fuller, W., & Shattock M.J. (2013). Novel regulation of cardiac Na pump via phospholemman. J Mol Cell Cardiol 61 pp 83-93. Pavlovic, D., Hall, A., Kennington, E.J., Aughton, K., Boguslavskyii, A., Fuller, W., Despa, S., Bers, D.M. & Shattock M.J. (2013). Rapid Pacing Stimulates Na/K ATPase in Rat Ventricular Myocytes via a Nitric Oxide and Phospholemman-dependent Mechanism. J Mol Cell Cardiol 61 pp 164-71. Wypijewski K., Howie, J., Reilly, L., Tulloch, L.B., Aughton, K.L., McLatchie, L.M., Shattock, M.J., Calaghan SC, &. Fuller, W. (2013). A separate pool of cardiac phospholemman that does not regulate or associate with the sodium pump: multimers of phospholemman in ventricular muscle. J Biol Chem 288 pp 13808-20. Corresponding author. Howie, J., Tulloch, L., Shattock, M.J. & Fuller W. (2013). Regulation of the Cardiac Sodium Pump by Palmitoylation of its Catalytic and Regulatory Subunits. Biochemical Society Transactions 41 pp 95-100. Corresponding author. Fuller, W., Tulloch, L., Shattock, M.J., Calaghan, S.C., Howie, J. & Wypijewski K. (2013). Regulation of the cardiac sodium pump. Cellular & Molecular Life Sciences 70 pp 1357-80. Corresponding author. Tulloch, L., Howie, J., Wilson, C., Wypijewski, K., Bernard, W., Shattock, M.J. & Fuller W. (2011). The inhibitory effect of phospholemman on the sodium pump requires its palmitoylation. J. Biol Chem 286 pp 36020-36031. Corresponding author. El Armouche, A., Wittk?pper, K., Howie, J., Fuller, W., Shattock, M.J. & Pavlovic, D. (2011). Phospholemman-dependent regulation of the cardiac Na/K-ATPase activity is modulated by inhibitor-1 sensitive type-1 phosphatase. FASEB J 25 pp 4467-4475. Wypijewski K, Shattock MJ and Fuller W (2010). Phospholemman Migrates out of Cardiomyocyte Caveolae upon Protein Kinase C Activation. Circulation 122 A21319. Selected for oral presentation at American Heart Association annual meeting, Chicago, 2010. Howie J, Tulloch LB, Beddie E, Shattock, MJ and Fuller W (2010) Peroxiredoxin 6 is Recruited to the Cardiac Sodium Pump Complex by Phospholemman. Circulation 122 A21311. Selected for poster presentation at American Heart Association annual meeting, Chicago, 2010. Madhani M, Hall AR, Cuello F, Charles RL, Burgoyne JR, Fuller W, Hobbs AJ, Shattock MJ, Eaton P. (2010) Phospholemman Ser-69 phosphorylation contributes to sildenafil-induced cardioprotection against reperfusion injury. Am J Physiol 299(3):H827-3. Fuller W, Howie J, McLatchie LM, Weber RJ, Hastie CJ, Burness K, Pavlovic D, Shattock MJ (2009) FXYD1 phosphorylation in vitro and in adult rat cardiac myocytes: threonine 69 is a novel substrate for protein kinase C. Am J Physiol Cell Physiol. 296:C1346-55. Bell JR, Kennington E, Fuller W, Dighe K, Donoghue P, Clark JE, Jia LG, Tucker AL, Moorman JR, Marber MS, Eaton P, Dunn MJ, Shattock MJ (2008) Characterization of the phospholemman knockout mouse heart: depressed left ventricular function with increased Na-K-ATPase activity. Am J Physiol Heart Circ Physiol. 294:H613-21. Pavlovi? D, Fuller W, Shattock MJ (2007) The intracellular region of FXYD1 is sufficient to regulate cardiac Na/K ATPase. FASEB J. 21:1539-46. Berry RG, Despa S, Fuller W, Bers DM, Shattock MJ (2007) Differential distribution and regulation of mouse cardiac Na/K-ATPase a1 and a2 subunits in T-tubule and surface sarcolemmal membranes. Cardiovasc Res. 73:92-100. Fuller W, Shattock MJ (2006) Phospholemman and the cardiac sodium pump: protein kinase C, take a bow. Circ Res. 99:1290-2.