Cohen, Sir Philip
Professor
所属大学: University of Dundee
所属学院: School of Life Sciences
近期论文
Emmerich, C. H., Ordureau, A., Strickson, S., Arthur, J. S., Pedrioli, P. G., Komander, D. and Cohen, P. (2013). Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains. Proc Natl Acad Sci U S A 110, 15247-15252 Pauls, E., Nanda, S. K., Smith, H., Toth, R., Arthur, J. S. and Cohen, P. (2013). Two Phases of Inflammatory Mediator Production Defined by the Study of IRAK2 and IRAK1 Knock-in Mice. J Immunol 191, 2717-2730 Goh, E. T. H., Arthur, J. S. C., Cheung, P. C. F., Akira, S., Toth, R., and Cohen, P. (2012) Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system Biochem. J. 441, 339-346 Smith, H., Liu, X-Y., Dai, L., Goh, E.T.H., Chan, A-T., Xi, J., She, C-C., Qureshi, I.A., Ruedl, C., Gourlay, R., Morton, S., Hough, J., McIver, E.G., Cohen, P. and Cheung, P.C.F. (2011) The role of TBK1 and IKKε in the expression and activation of Pellino 1. Biochem. J. 434, 537-548 Enesa, K., Ordureau, A., Smith, H., Barford, D., Cheung, P.F.C., Arthur, J.S., and Cohen, P. (2012) Pellino1 is required for interferon production by viral double-stranded RNA. J. Biol. Chem. 287, 34825-34835 Ordureau, A., Enesa, K., Nanda, S., Le Francois, B., Peggie, M., Prescott, A., Albert, P. R. and Cohen, P. (2013). DEAF1 Is a Pellino1-interacting Protein Required for Interferon Production by Sendai Virus and Double-stranded RNA. J Biol Chem 288, 24569-24580 Clark, K., Peggie, M., Plater, L., Sorcek, R.J., Young, E.R.R., Madwed, J.B., Hough, J., McIver, E.G. and Cohen, P. (2011) Novel cross-talk within the IKK family controls innate immunity. Biochem. J. 434, 93-104 Clark, K., Takeuchi, O., Akira, S. and Cohen, P. (2011) TANK facilitates crosstalk within the IKK family during TLR signaling. Proc. Natl. Acad. Sci. USA. 108, 17093-17098 Nanda, S.K., Venigalla, R.K.C., Ordureau, A., Patterson-Kane, J.C., Powell, D.W., Toth, R.J., Arthur, J.S.C. and Cohen, P. (2011) Polyubiquitin binding to ABIN1 is required to prevent autoimmunity J. Exp. Med. 208, 1215-1228 Gleason, C.E., Ordureau, A., Gourlay, R., Arthur, J.S.C. and Cohen , P. (2011) Polyubiquitin binding to optineurin is required for optimal activation of TANK-binding kinase 1 and the production of interferon β J. Biol. Chem. 286, 35663-35674 Clark, K., Nanda, S. and Cohen, P. (2013). Molecular control of the NEMO family of ubiquitin-binding proteins. Nat Rev Mol Cell Biol Clark, K., MacKenzie, K.F., Petkevicius, K., Kristariyonto,Y., Zhang, J., Choi, H.G., Peggie, M., Plater, L., Pedrioli, P.G.A., McIver, E., Gray, N.S., Arthur, J.S.C. and Cohen, P. (2012) Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages Proc Natl Acad Sci USA 109, 16986-16991