Steger, M., Tonelli, F., Ito, G., Davies, P., Trost, M., Vetter, M., Wachter, S., Lorentzen, E., Duddy, G., Wilson, S., Baptista, M.A.S., Fiske, B.K., Fell, M.J., Morrow, J.A., Reith, A.D., Alessi, D. R. and Mann, M. (2016) Phosphoproteomics reveals that Parkinson’s disease kinase LRRK2 regulates a subset of Rab GTPases. eLife DOI: http://dx.doi.org/10.7554/eLife.12813 [Dario Alessi and Matthias Mann Joint corresponding authors] Zhang, N., Gordon, S.L., Fritsch, M.J., Esoof, N., Campbell, D.G., Gourlay, R., Velupillai, S., Macartney, T., Peggie, M., van Aalten, D.M.F., Cousin, M.A. Dario R. Alessi and Alessi, D. R. (2015) Phosphorylation of SV2A at Thr84 by CK1 family kinases controls the specific retrieval of synaptotagmin-1. Journal of Neuroscience 35, 2492-250. Zhang, J, Siew, K, Macartney, T, O'Shaughnessy, K,M, Alessi, D. R. (2015) Critical role of the SPAK protein kinase CCT domain in controlling blood pressure. Hum Mol Genet. 24, 4545-4558 Perez-Oliva, A.B., Lachaud, C., Szyniarowski, P., Mu?oz, I., Macartney, T., Hickson, I., Rouse, R., and Alessi, D. R. (2015) USP45 deubiquitylase controls ERCC1-XPF endonuclease mediated DNA damage responses. EMBO J. 34, 326-343. Bago, R., Malik, N., Munson, M.J., Prescott, A.R., Davies, P., Sommer, E., Shpiro, N., Ward, R., Cross, D., Ganley, I.G and Alessi, D. R. (2014) Characterisation of VPS34-IN1, a selective inhibitor of Vps34 reveals that the phosphatidylinositol 3-phosphate binding SGK3 protein kinase is a downstream target of Class III PI-3 kinase. Biochemical J 463, 413-427. Alessi, D. R., Zhang, J., Khanna, A., Hochd?rfer, T., Shang, Y., and Kahle, K.T. (2014) The WNK-SPAK/OSR1 pathway: Master regulator of cation-chloride cotransporters. Science signalling 7, Re3 Banerjee S., Zagorska A., Deak M., Campbell D.G., Prescott A., and Alessi, D. R. (2014) Interplay between Polo kinase, LKB1-activated NUAK1 kinase, PP1βMYPT1 phosphatase complex and the SCFβTrCP E3 ubiquitin ligase. Biochemical J 461, 233-245. van der Wijst, J., Blanchard, M.G., Woodroof, H.I., Macartney, T.J., Gourlay, R., Hoenderop, J.G., Bindels, R.J., and Alessi, D. R. (2014) Kinase and channel activity of TRPM6 are coordinated by a dimerization motif and pocket interaction. Biochemical Journal. 460,165-175. Houde, V,P., Ritorto, M,S., Gourlay,. R, Varghese, J., Davies, P., Shpiro, N., Sakamoto, K. and Alessi, D. R. (2014) Investigation of role that LKB1 Ser431 phosphorylation and Cys433 farnesylation play by mouse knock-in analysis reveals an unexpected role of prenylation in regulating AMPK activity. Biochemical Journal 458, 41-56. Sommer, E.M., Dry, H., Cross, D., Guichard, S., Davies, B.R. and Alessi, D. R. (2013) Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitors. Biochemical Journal 452, 499-508.