B.S. Rensselaer Polytechnic Institute Physics M.D. State University of New York, Downstate Medical Center Medicine

Runx1 regulates myeloid precursor differentiation into osteoclasts without affecting differentiation into antigen presenting or phagocytic cells in both males and females.Paglia, David N; Yang, Xiaochuan; Kalinowski, Judith; Jastrzebski, Sandra; Drissi, Hicham; Lorenzo, Joseph Endocrinology 2016 Jun;en20152037 Serum Amyloid A3 Secreted by Preosteoclasts Inhibits Parathyroid Hormone-Stimulated cAMP Signaling in Murine Osteoblasts.Choudhary, Shilpa; Goetjen, Alexandra; Estus, Thomas; Jacome-Galarza, Christian E; Aguila, Hector L; Lorenzo, Joseph; Pilbeam, Carol The Journal of biological chemistry 2015 Dec; Loss of Cbl-PI3K interaction in mice prevents significant bone loss following ovariectomy.Adapala, Naga Suresh; Holland, Danielle; Scanlon, Vanessa; Barbe, Mary F; Langdon, Wallace Y; Tsygankov, Alexander Y; Lorenzo, Joseph A; Sanjay, Archana Bone 2014 Jul;671-9 Runx1-mediated regulation of osteoclast differentiation and function.Soung, Do Y; Kalinowski, Judith; Baniwal, Sanjeev K; Jacome-Galarza, Christian E; Frenkel, Baruch; Lorenzo, Joseph; Drissi, Hicham Molecular endocrinology (Baltimore, Md.) 2014 Apr;28(4):546-53 Altered hematopoietic stem cell and osteoclast precursor frequency in cathepsin K null mice.Jacome-Galarza, Christian; Soung, Do Yu; Adapala, Naga Suresh; Pickarski, Maureen; Sanjay, Archana; Duong, Le T; Lorenzo, Joseph A; Drissi, Hicham Journal of cellular biochemistry 2014 Mar;115(8):1449-57 Loss of Cbl-PI3K interaction enhances osteoclast survival due to p21-Ras mediated PI3K activation independent of Cbl-b.Adapala, Naga Suresh; Barbe, Mary F; Tsygankov, Alexander Y; Lorenzo, Joseph A; Sanjay, Archana Journal of cellular biochemistry 2014 Jan;115(7):1277-89 Identification, characterization, and isolation of a common progenitor for osteoclasts, macrophages, and dendritic cells from murine bone marrow and periphery.Jacome-Galarza, Christian E; Lee, Sun-Kyeong; Lorenzo, Joseph A; Aguila, Hector Leonardo Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 May;28(5):1203-13 Changes in bone sclerostin levels in mice after ovariectomy vary independently of changes in serum sclerostin levels.Jastrzebski, Sandra; Kalinowski, Judith; Stolina, Marina; Mirza, Faryal; Torreggiani, Elena; Kalajzic, Ivo; Won, Hee Yeon; Lee, Sun-Kyeong; Lorenzo, Joseph Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 Mar;28(3):618-26 Negative regulation of osteoclast precursor differentiation by CD11b and β2 integrin-B-cell lymphoma 6 signaling.Park-Min, Kyung-Hyun; Lee, Eun Young; Moskowitz, Neal K; Lim, Elisha; Lee, Sun-Kyeong; Lorenzo, Joseph A; Huang, Chuanxin; Melnick, Ari M; Purdue, P Edward; Goldring, Steven R; Ivashkiv, Lionel B Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 Jan;28(1):135-49 Osteoblast-specific overexpression of human interleukin-7 rescues the bone mass phenotype of interleukin-7-deficient female mice.Aguila, Hector L; Mun, Se Hwan; Kalinowski, Judith; Adams, Douglas J; Lorenzo, Joseph A; Lee, Sun-Kyeong Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2012 May;27(5):1030-42 Long-term treatment with raloxifene, but not bisphosphonates, reduces circulating sclerostin levels in postmenopausal women.Chung, Y E; Lee, S H; Lee, S-Y; Kim, S-Y; Kim, H-H; Mirza, F S; Lee, S-K; Lorenzo, J A; Kim, G S; Koh, J-M Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2012 Apr;23(4):1235-43 Parathyroid hormone regulates the distribution and osteoclastogenic potential of hematopoietic progenitors in the bone marrow.Jacome-Galarza, Christian E; Lee, Sun-Kyeong; Lorenzo, Joseph A; Aguila, Hector Leonardo Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011 Jun;26(6):1207-16 How B cells influence bone biology in health and disease.Horowitz, Mark C; Fretz, Jackie A; Lorenzo, Joseph A Bone 2010 Sep;47(3):472-9 Immature osteoblast lineage cells increase osteoclastogenesis in osteogenesis imperfecta murine.Li, Haitao; Jiang, Xi; Delaney, John; Franceschetti, Tiziana; Bilic-Curcic, Ines; Kalinovsky, Judy; Lorenzo, Joseph A; Grcevic, Danka; Rowe, David W; Kalajzic, Ivo The American journal of pathology 2010 May;176(5):2405-13 Serum sclerostin levels negatively correlate with parathyroid hormone levels and free estrogen index in postmenopausal women.Mirza, Faryal S; Padhi, I Desmond; Raisz, Lawrence G; Lorenzo, Joseph A The Journal of clinical endocrinology and metabolism 2010 Apr;95(4):1991-7 Nuclear isoforms of fibroblast growth factor 2 are novel inducers of hypophosphatemia via modulation of FGF23 and KLOTHO.Xiao, Liping; Naganawa, Takahiro; Lorenzo, Joseph; Carpenter, Thomas O; Coffin, J Douglas; Hurley, Marja M The Journal of biological chemistry 2010 Jan;285(4):2834-46 Ebf1-dependent control of the osteoblast and adipocyte lineages.Hesslein, David G T; Fretz, Jackie A; Xi, Yougen; Nelson, Tracy; Zhou, Shoaming; Lorenzo, Joseph A; Schatz, David G; Horowitz, Mark C Bone 2009 Apr;44(4):537-46 Accentuated osteoclastic response to parathyroid hormone undermines bone mass acquisition in osteonectin-null mice.Machado do Reis, Luciene; Kessler, Catherine B; Adams, Douglas J; Lorenzo, Joseph; Jorgetti, Vanda; Delany, Anne M Bone 2008 Aug;43(2):264-73 Estradiol rapidly inhibits osteoclastogenesis and RANKL expression in bone marrow cultures in postmenopausal women: a pilot study.Taxel, P; Kaneko, H; Lee, S-K; Aguila, H L; Raisz, L G; Lorenzo, J A Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2008 Feb;19(2):193-9 v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation.Lee, Seoung-Hoon; Rho, Jaerang; Jeong, Daewon; Sul, Jai-Yoon; Kim, Taesoo; Kim, Nacksung; Kang, Ju-Seob; Miyamoto, Takeshi; Suda, Toshio; Lee, Sun-Kyeong; Pignolo, Robert J; Koczon-Jaremko, Boguslawa; Lorenzo, Joseph; Choi, Yongwon Nature medicine 2006 Dec;12(12):1403-9 Megakaryocyte-mediated inhibition of osteoclast development.Kacena, Melissa A; Nelson, Tracy; Clough, Mary E; Lee, Sun-Kyeong; Lorenzo, Joseph A; Gundberg, Caren M; Horowitz, Mark C Bone 2006 Nov;39(5):991-9 T lymphocyte-deficient mice lose trabecular bone mass with ovariectomy.Lee, Sun-Kyeong; Kadono, Yuho; Okada, Fumihiko; Jacquin, Claire; Koczon-Jaremko, Boguslawa; Gronowicz, Gloria; Adams, Douglas J; Aguila, Hector L; Choi, Yongwon; Lorenzo, Joseph A Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006 Nov;21(11):1704-12 Congenic mice provide in vivo evidence for a genetic locus that modulates serum insulin-like growth factor-I and bone acquisition.Delahunty, K M; Shultz, K L; Gronowicz, G A; Koczon-Jaremko, B; Adamo, M L; Horton, L G; Lorenzo, J; Donahue, L R; Ackert-Bicknell, C; Kream, B E; Beamer, W G; Rosen, C J Endocrinology 2006 Aug;147(8):3915-23 Interleukin-7 influences osteoclast function in vivo but is not a critical factor in ovariectomy-induced bone loss.Lee, Sun-Kyeong; Kalinowski, Judith F; Jacquin, Claire; Adams, Douglas J; Gronowicz, Gloria; Lorenzo, Joseph A Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006 May;21(5):695-702