Cech, Thomas
Professor
所属大学: University of Colorado
所属学院: Chemistry and Biochemistry
个人简介
Ph.D.: University of California, Berkeley, 1975
研究领域
Nucleic Acids
近期论文
Baumann, P. and Cech, T. R. Pot1, the Putative Telomere End-binding Protein in Fission Yeast and Humans. Science 292, 1171-1175 (2001). Lei, M., Podell, E. R., Baumann, P. and Cech, T. R. DNA Self-recognition in the Structure of Pot1 Bound to Telomeric Single-stranded DNA. Nature 426, 198-203 (2003). Pfingsten, J.S., Goodrich, K.J., Taabazuing, C., Ouenzar, F., Chartrand, P., Cech, T.R. Mutually Exclusive Binding of Telomerase RNA and DNA by Ku Alters telomerase recruitment Model. Cell, 148, 922-932 (2012). Nandakumar, J., Bell, C.F., Weidenfeld, I., Zaug, A.J., Leinwand, L.A., Cech, T.R. The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity. Nature, 492: 285-289 (2012). Schwartz, J.C., Ebmeier, C.C., Podell, E.R., Heimiller, J., Taatjes, D.J., Cech, T.R. FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2. Genes Dev. 26: 2690-95 (2012).