COLE, ALEXANDER M.
Professor
所属大学: University of Central Florida
所属学院: Division of Molecular Microbiology
邮箱:
acole@ucf.edu
个人主页:
https://med.ucf.edu/biomed/directory/dr-alexander-m-cole/
近期论文
Sivaraman, K., A.M. Cole. (2009). Pathogenesis gene families in the common minimal genome of Staphylococcus aureus are hypervariable. FEBS Letters. 583(8): 1304-8. (PMCID: PMC2677416) Martellini, J.A., A.L. Cole, N. Venkataraman, G.A. Quinn, P. Svoboda, B.K. Gangrade, J. Pohl, O.E. S?rensen, and A.M. Cole. (2009). Cationic polypeptides are major anti-HIV-1 factors in human seminal plasma. FASEB J. 23(10): 3609-18. NIHMS# 219133 Quinn, G.A., P.M. Tarwater, and A.M. Cole. (2009). Subversion of IL-1-mediated host defense by a nasal carrier strain of Staphylococcus aureus. Immunology. 128: e222-229. (PMCID: PMC2753939) Venkataraman, N., A.L. Cole, P. Ruchula, A.J. Waring, R.I. Lehrer, O. Stuchlik, J. Pohl, and A.M. Cole. (2009). Reawakening retrocyclins: ancestral human theta-defensins with activity against HIV-1. PLoS Biology. 7(4): e95. (PMCID: PMC2672613). (received Editor’s pick, and was selected for a commissioned synopsis) Cole, A.M., D.L. Patton, L.C. Rohan, A.L. Cole, Y. Cosgrove-Sweeney, N.A. Rogers, D. Ratner, A. Sassi, P. Tarwater, B. Ramratnam, P. Ruchala, R.I. Lehrer, A.J. Waring, and P. Gupta. (2010). The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques. PLoS ONE. 5(11): e15111. (PMCID: PMC2993972) Micewicz E.D., A.L. Cole, C.L. Jung, H. Luong, M.L. Phillips, P. Pratikhya, S. Sharma, A.J. Waring, A.M. Cole, and P. Ruchala. (2010). Grifonin-1: a small HIV-1 entry inhibitor derived from the algal lectin, Griffithsin. PLoS ONE. 5(12): e14360. (PMCID: PMC3002932) Lamers, R.P., J.W. Stinnett, G. Muthukrishnan, C.L. Parkinson, and A.M. Cole. (2011). Evolutionary analyses of Staphylococcus aureus reveal that human nares harbor strains responsible for community- and hospital-acquired infections. PLoS ONE 6(1): e16426. (PMCID: PMC3025037) Martellini, J.A., A.L. Cole, P. Svoboda, O. Stuchlik, L.M. Chen, K.X. Chai, B.K. Gangrade, O.E. S?rensen, J. Pohl, and A.M. Cole. (2011). HIV-1 enhancing effect of prostatic acid phosphatase peptides is reduced in human seminal plasma. PLoS ONE. 6(1): e16285. (PMCID: PMC3024420) Sassi, A.B., M.R. Cost, A.L. Cole, A.M. Cole, D.L. Patton, P. Gupta and L.C. Rohan. (2011). Formulation development of Retrocyclin-1 (RC-101) as an anti-HIV vaginal microbicide product. Antimicrob Agents Chemother. 55(5): 2282-9. (PMCID: PMC3088226) Muthukrishnan, G., G.A. Quinn, R.P. Lamers, C. Diaz, A.L. Cole, S. Chen, and A.M. Cole. (2011). Exoproteome of Staphylococcus aureus reveals putative determinants of nasal carriage. J Proteome Res. 10(4): 2064-78. (PMCID: PMC3070068) Sassi, A.B., K.E. Bunge, B.L. Hood, T.P. Conrads, A.M. Cole, P. Gupta, and L.C. Rohan. (2011). Preformulation and stability in biological fluids of the retrocyclin RC-101, a potential anti-HIV topical microbicide. AIDS Res Ther. 8(27): (Epub ahead of print). (PMCID: PMC3199744) Lamers, R.P., C.R. Eade, A.J. Waring, A.L. Cole, and A.M. Cole. (2011). Characterization of the retrocyclin analogue RC-101 as a preventative of Staphylococcus aureus nasal colonization. Antimicrob Agents Chemother. 55(11): 5338-46. (PMCID: PMC3195007) Ruchala, P., S. Cho, A.L. Cole, C. Carpenter, C.L. Jung, H. Luong, E.D. Micewicz, A.J. Waring, A.M. Cole, B.C. Herold, and R.I. Lehrer. (2011). Simplified theta-defensins: search for new antivirals. Int J Pept Res Ther. 17(4): 325-336. Li, M., D.L. Patton, Y. Cosgrove-Sweeney, D. Ratner, L.C. Rohan, A.M. Cole, P. Tarwater, P. Gupta, and B. Ramratnam. (2011). Incorporation of the HIV-1 microbicide cyanovirin-N in a food product. J AIDS. 58(4): 379-384. (PMCID: PMC3440868) Levinson, P., R.Y. Choi, A.L. Cole, T. Hirbod, S. Rhedin, B. Payne, B. Guthrie, R. Bosire, A.M. Cole, C. Farquhar, and K. Broliden. (2012). HIV-neutralizing activity of cationic polypeptides in cervicovaginal secretions of women in HIV-serodiscordant relationships. PLoS ONE. 7(2): e31996. (PMCID: PMC3289637) A.M.L. Edstr?m, V. Rydengard, P. Fernlund, M. Morgelin, M. Baungarten, A.M. Cole, M. Malmsten, B.B. Karglund, O.E. S?rensen. (2012). beta-microseminoprotein endows seminal plasma with potent calcium-dependent candidacidal activity at vaginal pH. PLoS Pathogens. 8(4): e1002625. (PMCID: PMC3320615) Gupta, P., D. Ratner, M. Ding, B. Patterson, L.C. Rohan, T. Reinhart, V. Ayyavoo, X. Huang, D.L. Patton, B. Ramratnam, and A.M. Cole. (2012). Retrocyclin RC-101 blocks HIV-1 transmission across cervical mucosa in an organ culture. J AIDS. 60(5):455-461. (PMCID: PMC3404240) Gupta, P., C. Lackman-Smith, D. Ratner, L.C. Rohan, D.L. Patton, B. Ramratnam, and A.M. Cole. (2012). Antiviral activity of retrocyclin RC-101, a candidate microbicide against cell-associated HIV-1. AIDS Res Hum Retroviruses. 29(2): 391-6. (PMCID: PMC3552163) Lamers, R.P., G. Muthukrishnan, T. A. Castoe, S. Tafur, A.M. Cole*, and C.L. Parkinson*. (2012). Phylogenetic relationships among Staphylococcus species and refinement of cluster groups based on multilocus data. BMC Evol Biol. 12: 171. (PMCID: PMC3464590) *Equal correspondence/authorship. Designated “Highly accessed” article by BMC. Eade, C.R., C. Diaz, M.P. Wood, K. Anastos, B.K. Patterson, P. Gupta, A.L. Cole, and A.M. Cole. (2012). Identification and Characterization of Bacterial Vaginosis-Associated Pathogens Using a Comprehensive Cervical-Vaginal Epithelial Coculture Assay. PLoS ONE. 7(11): e50106. (PMCID: PMC3499514) Eade, C.R., A.L. Cole, C. Diaz, L.C. Rohan, M.A. Parniak, P. Marx, P.M. Tarwater, P. Gupta, and A.M. Cole. (2013). The Anti-HIV Microbicide Candidate RC-101 Inhibits Pathogenic Vaginal Bacteria Without Harming Endogenous Flora or Mucosa. Am J Reprod Immunol. 69(2):150-8. (PMCID: PMC3541468) Wood, M.P., A.L. Cole, P. Ruchala, A.J. Waring, L.C. Rohan, P. Marx, P.M. Tarwater, P. Gupta, and A.M. Cole. (2013). A Compensatory Mutation Provides Resistance to Disparate HIV Fusion Inhibitor Peptides and Enhances Membrane Fusion. PLoS ONE. 8(2):e55478. (PMCID: PMC3564752) Muthukrishnan, G., R.P. Lamers, A. Ellis, V. Paramanandam, A.B. Persaud, S. Tafur, C.L. Parkinson, and A.M. Cole. (2013). Longitudinal genetic analyses of Staphylococcus aureus nasal carriage dynamics in a diverse population. BMC Infect Dis. 16(13): 221. (PMCID: PMC3673815) Wood, M.P., A.L. Cole, C.R. Eade, L.M. Chen, K.X. Chai, and A.M. Cole. (2014). The HIV-1 gp41 ectodomain is cleaved by matriptase to produce a chemotactic peptide that acts through FPR2. Immunology. (in press)