Prof. Guy C. Brown received his Ph.D. in 1986 from the Biochemistry Department at Cambridge, then had a College Research Fellowship from St Catharine's College for 3 years. He then moved to the Department of Physiology, University College London, with a Wellcome Trust Post-doctoral Fellowship, and after 18 months transferred to a Royal Society Research Fellowship at the Department of Biochemistry at UCL. In 1994 he returned to Cambridge with the Royal Society Research Fellowship, and is now a Professor of Cellular Biochemistry at the Department of Biochemistry, University of Cambridge. He has published about 150 scientific papers. His research has been funded by: the Medical Research Council, the Biotechnology & Biological Sciences Research Council, the European Union, the Wellcome Trust, the British Heart Foundation, and Alzheimer’s Research UK.

Neher JJ, Emmrich JV, Fricker M, Mander PK, Thery C, Brown GC (2013) Phagocytosis executes delayed neuronal death after focal brain ischemia. Proc Natl Acad Sci 110:E4098-107. Hornik TC, Neniskyte U & Brown GC (2013) Inflammation induces Multinucleation of Microglia via PKC inhibition of Cytokinesis, generating highly phagocytic Multinucleated Giant Cells. J. Neurochem. In press Emmrich J. Hornik T Neher J & Brown GC (2013) Rotenone induces neuronal death by microglial phagocytosis of neurons. FEBS J. 280, 5030-5038. Fricker M, Vilalta A, Tolkovsky AM, Brown GC (2013) Caspase inhibitors protect neurons by enabling selective necroptosis of inflamed microglia. J Biol Chem. 288, 9145-52. Neniskyte U, Brown GC (2013) Lactadherin/MFG-E8 is essential for microglia-mediated neuronal loss and phagoptosis induced by amyloid β. J Neurochem. 126, 312-7. Brown GC & Neher JJ (2012) Eaten alive! Cell death by primary phagocytosis: ‘phagoptosis’. Trends Biochem. Sci. 37, 325-332. Fricker M, Neher JJ, Zhao JW, Théry C, Tolkovsky AM, Brown GC (2012) MFG-E8 Mediates Primary Phagocytosis of Viable Neurons during Neuroinflammation. J Neurosci. 32, 2657-66. Fricker M, Oliva-Martin MJ, Brown GC (2012) Primary phagocytosis of viable neurons by microglia activated with LPS or Abeta is dependent on calreticulin/LRP phagocytic signalling. Journal of Neuroinflammation, 13, 9. Neher JJ, Neniskyte U, Zhao ZW, Bal-Price A, Tolkovsky AM & Brown GC (2011) Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death. J Immunol. 186, 4973-83. Barauskaite J, Grybauskiene R, Morkuniene R, Borutaite V, Brown GC (2011) Tetramethylphenylenediamine protects the isolated heart against ischaemia-induced apoptosis and reperfusion-induced necrosis. Br J Pharmacol. 162:1136-42.