NMR spectroscopy, DNA-binding proteins, membrane proteins, cancer

Feinstein, HE, Tifrea, DF, Popot, J-L, de la Maza, LM, Cocco, MJ*. (2014) Long-term stability of a vaccine formulated with the amphipol-trapped major outer membrane protein from Chlamydia trachomatis. J. Membrane Biology, in press Alhoshani, A,Vithayathil R, Bandong J, Chrunyk, KM, Moreno, GO, Weiss, GA and Cocco, MJ*. (2014) Glutamate is a Key Structural Contact Between Nogo-66 and Phosphocholine. BBA – Biomembranes, 1838: 2350-6 Tifrea, DF, Pal, S, Cocco, MJ, Popot, J-L and de la Maza, LM. Increased immuno accessibility of MOMP epitopes in a vaccine formulated with amphipols may account for the very robust protection elicited against a vaginal challenge with C. muridarum. (2014) J. Immunology 192: 5201-13 Vithayathil R, Hooy RM, Cocco MJ, Weiss GA. (2011) The Scope of phage display for membrane proteins. J. Mol. Biol. 414:499-510 Popot JL, Althoff T, Bagnard D, Banères JL, Bazzacco P, Billon-Denis E, Catoire LJ, Champeil P, Charvolin D, Cocco MJ, Crémel G, Dahmane T, de la Maza LM, Ebel C, Gabel F, Giusti F, Gohon Y, Goormaghtigh E, Guittet E, Kleinschmidt JH, Kühlbrandt W, Le Bon C, Martinez KL, Picard M, Pucci B, Sachs JN, Tribet C, van Heijenoort C, Wien F, Zito F, Zoonens M. (2011) Amphipols from A to Z. Annu Rev Biophys. 2011 40:379-408 Moody, CL, Tretyachenko-Ladokhina, V, Laue, T., Senear, DF and Cocco, MJ* (2011) Multiple Conformations of the Cytidine Repressor DNA-Binding Domain Coalesce to One Upon Recognition of a Specific DNA Surface. Biochemistry, 50:6622-32 Tifrea, DF, Sun, G, Pal, S, Zardeneta1, G, Cocco, MJ, Popot, J-L, de la Maza, LM (2011) Amphipols stabilize the Chlamydia major outer membrane protein and enhance vaccine protection based on a membrane-protein formulation. Vaccine 29:4623-31 Corbin-Lickfett, KA, Souki, SK, Li, L, Cocco, MJ and Sandri-Goldin, RM. (2010) Three arginine residues within the RGG-box are crucial for ICP27 binding to herpes simplex virus 1 GC-rich sequences and for efficient viral RNA export. Journal of Virology, 84:6367-76 Vasudevan, SV, Schulz, J, Zhou, C and Cocco, MJ*. (2010) Protein Folding at the Membrane Interface, the Structure of Nogo-66. Proceedings of the National Academy of Sciences, 107:6847-51