Neurophysiological computations and mechanisms that mediate human vision, particularly changes in vision across the life span and in diseases of the retina and optic nerve. Current studies use psychophysical and electrophysiological methods, together with high-resolution retinal imaging (adaptive optics and optical coherence tomography), to study both normal aging and age-related diseases leading to blindness.

Shinomori, K. & Werner, J.S. (2012) Aging of human short-wave cone pathways. Proceedings of the National Academy of Sciences USA, 109, 13422-13427. Kim, D.Y., Fingler, J., Zawadzki, R.J., Park, S.S., Morse, L.S., Schwartz, D.M., Fraser, S.E. & Werner, J.S. (2013) Optical imaging of the chorioretinal vasculature in the living eye. Proceedings of the National Academy of Sciences USA, 110, 14354-14359. Schwartz, D.M., Fingler, J., Kim, D.Y., Zawadzki, R.J., Morse, L.S., Park, S.S., Fraser, S.E. & Werner, J.S. (2014) Phase-variance optical coherence tomography: A technique for non-invasive angiography. Ophthalmology, 121, 180-187.