Renal Cell Signaling

Rigothier, CC, Saleem, MA, Bourget, C, Mathieson, PW, Combe, C & Welsh, GI, 2016, ‘Nuclear translocation of IQGAP1 protein upon exposure to puromycin aminonucleoside in cultured human podocytes: ERK pathway involvement’. Cellular Signalling, vol 28., pp. 1470-1478 Salakhieva, D, Sadreev, I, Chen, M, Umezawa, Y, Evstifeev, A, Welsh, G & Kotov, N, 2016, ‘Kinetic regulation of multi-ligand binding proteins’. BMC Systems Biology, vol 10. Rollason, R, Wherlock, MD, Heath, JA, Heesom, KJ, Saleem, M & Welsh, GI, 2016, ‘Disease causing mutations in inverted formin 2 regulate its binding to G-actin, F-actin capping protein (CapZ α-1) and profilin 2’. Bioscience Reports, vol 36. Santamaria, B, Marquez, E, Lay, A, Carew, RM, González-Rodríguez, &#x, We;lsh, GI, Ni, L, Hale, LJ, Ortiz, A, Saleem, MA, Brazil, DP, Coward, RJ & Valverde, &#xM, ;2015, ‘IRS2 and PTEN are key molecules in controlling insulin sensitivity in podocytes’. Biochim Biophys Acta. Kumar, PA, Welsh, GI, Raghu, G, Menon, RK, Saleem, MA & Reddy, GB, 2015, ‘Carboxymethyl lysine induces EMT in podocytes through transcription factor ZEB2: Implications for podocyte depletion and proteinuria in diabetes mellitus’. Archives of Biochemistry and Biophysics, vol 590., pp. 10-19 Jiang, L, Dasgupta, I, Hurcombe, JA, Colyer, HF, Mathieson, PW & Welsh, GI, 2015, ‘Levamisole in steroid-sensitive nephrotic syndrome: usefulness in adult patients and laboratory insights into mechanisms of action via direct action on the kidney podocyte’. Clinical Science. Lennon, R, Stuart, HM, Bierzynska, A, Randles, MJ, Kerr, B, Hillman, KA, Batra, G, Campbell, J, Storey, H, Flinter, FA, Koziell, A, Welsh, GI, Saleem, MA, Webb, NJA & Woolf, AS, 2015, ‘Coinheritance of COL4A5 and MYO1E mutations accentuate the severity of kidney disease’. Pediatric Nephrology, vol 30., pp. 1459-65 Keir, LS, Firth, R, May, C, Ni, L, Welsh, GI & Saleem, MA, 2015, ‘Generating conditionally immortalised podocyte cell lines from wild-type mice’. Nephron, vol 129., pp. 128-36 Rhodes, HL, Yarram-Smith, L, Rice, SJ, Tabaksert, A, Edwards, N, Hartley, A, Woodward, MN, Smithson, SL, Tomson, C, Welsh, GI, Williams, M, Thwaites, DT, Sayer, JA & Coward, RJM, 2015, ‘Clinical and Genetic Analysis of Patients with Cystinuria in the United Kingdom’. Clinical journal of the American Society of Nephrology : CJASN. Ramnath, R, Foster, RR, Qiu, Y, Cope, G, Butler, MJ, Salmon, AH, Mathieson, PW, Coward, RJ, Welsh, GI & Satchell, SC, 2014, ‘Matrix metalloproteinase 9-mediated shedding of syndecan 4 in response to tumor necrosis factor α: a contributor to endothelial cell glycocalyx dysfunction’. 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