Molecular Epidemiology and Translational Research into Dementia therapeutics

Skrobot, O, Attems, J, Esiri, MM, Hortobágyi, T, Ironside, JW, Kalaria, R, King, A, Lammie, G, Mann, D, Neal, J, Ben-Shlomo, Y, Kehoe, P & Love, S, 2016, ‘Vascular cognitive impairment neuropathology guidelines (VCING)’. Brain. Skrobot, OA, McKnight, AJ, Passmore, PA, Seripa, D, Mecocci, P, Panza, F, Kalaria, R, Wilcock, GK, Munafò, MR, Erkinjuntti, T, Karhunen, P, Pessi, T, Martiskainen, M, Love, S, Kehoe, PG & , 2016, ‘A Validation Study of Vascular Cognitive Impairment Genetics Meta-Analysis Findings in an Independent Collaborative Cohort’. Journal of Alzheimer's Disease, vol 53., pp. 981-989 Barber, IS, Braae, A, Clement, N, Patel, T, Guetta-Baranes, T, Brookes, K, Medway, C, Chappell, S, Guerreiro, R, Bras, J, Hernandez, D, Singleton, A, Hardy, JRW, Mann, DM, Passmore, P, Craig, D, Johnston, J, McGuinness, B, Todd, S, Heun, R, Kölsch, H, Kehoe, PG, Vardy, ER, Hooper, NM, Pickering-Brown, S, Snowden, J, Richardson, A, Jones, M, Neary, D, Harris, J, Lowe, J, Smith, AD, Wilcock, GK, Warden, D, Holmes, C & Morgan, K, 2016, ‘Mutation Analysis of Sporadic Early-Onset Alzheimer’s Disease using the NeuroX Array’. Neurobiology of Aging. Love, S, Chalmers, K, Ince, P, Esiri, M, Attems, J, Kalaria, R, Jellinger, K, Yamada, M, McCarron, M, Minett, T, Matthews, F, Greenberg, S, Mann, D & Kehoe, PG, 2016, ‘Erratum: Development, appraisal, validation and implementation of a consensus protocol for the assessment of cerebral amyloid angiopathy in post-mortem brain tissue’. American journal of neurodegenerative disease, vol 4., pp. 49 Ashby, EL, Kierzkowska, M, Hull, J, Kehoe, PG, Hutson, SM & Conway, ME, 2016, ‘Altered Expression of Human Mitochondrial Branched Chain Aminotransferase in Dementia with Lewy Bodies and Vascular Dementia’. Neurochemical Research. Jochemsen, HM, Van Der Flier, WM, Ashby, EL, Teunissen, CE, Jones, RE, Wattjes, MP, Scheltens, P, Geerlings, MI, Kehoe, PG & Muller, M, 2015, ‘Angiotensin-converting enzyme in cerebrospinal fluid and risk of brain atrophy’. J Alzheimers Dis, vol 44., pp. 153-162 Graham, SF, Chevallier, OP, Elliott, CT, Hölscher, C, Johnston, J, McGuinness, B, Kehoe, PG, Passmore, AP & Green, BD, 2015, ‘Untargeted metabolomic analysis of human plasma indicates differentially affected polyamine and L-arginine metabolism in mild cognitive impairment subjects converting to Alzheimer's disease’. PloS one, vol 10. Pan, X, Bin Nasaruddin, M, Elliott, CT, McGuinness, B, Passmore, AP, Kehoe, PG, Hölscher, C, McClean, PL, Graham, SF & Green, BD, 2015, ‘Alzheimer's disease-like pathology has transient effects on the brain and blood metabolome’. Neurobiology of Aging, vol 38., pp. 151-163 Nasaruddin, ML, Hölscher, C, Kehoe, P, Graham, SF & Green, BD, 2015, ‘Wide-ranging alterations in the brain fatty acid complement of subjects with late Alzheimer’s disease as detected by GC-MS’. American Journal of Translational Research, vol 8., pp. 154-165 Hosp, F, Vossfeldt, H, Heinig, M, Vasiljevic, D, Arumughan, A, Wyler, E, , Landthaler, M, Hubner, N, Wanker, EE, Lannfelt, L, Ingelsson, M, Lalowski, M, Voigt, A, Selbach, M & Kehoe, P, 2015, ‘Quantitative interaction proteomics of neurodegenerative disease proteins’. Cell Reports, vol 11., pp. 1134-1146